Prospective evaluation of quality of surgery in soft tissue sarcoma

• Published in: European journal of surgical oncology 2006-12, Vol.32 (10), p.1242-1248
• Main Authors: Stoeckle, E., Gardet, H., Coindre, J.-M., Kantor, G., Bonichon, F., Milbéo, Y., Thomas, L., Avril, A., Bui, B.N.
• Format: Article
• Language: English
• Subjects: Adolescent; Adult; Aged; Aged, 80 and over; Combined Modality Therapy; Extremities; Female; French Sarcoma Group; Humans; Local recurrence; Male; Middle Aged; Neoplasm Recurrence, Local; Neoplasm, Residual; Prognosis; Prognostic factors; Risk Factors; Sarcoma - pathology; Sarcoma - surgery; Soft Tissue Neoplasms - pathology; Soft Tissue Neoplasms - surgery; Soft tissue sarcoma; Surgery
• ISSN: 0748-7983; 1532-2157
• DOI: 10.1016/j.ejso.2006.05.005

Prospective application of the French Sarcoma Group (FSG) method of surgery reporting in soft tissue sarcoma (STS) in a single centre. Patients with primary STS of the extremities or trunk wall consecutively operated at the same institution from January 1996 to December 2002 were evaluated for local recurrence (LR). There were 205 patients, with AJCC/UICC stages III and IV in 51% of cases. Resection types according to FSG were R0 in 147, R1 in 53 and R2 in five cases. Radiotherapy was delivered in 163 patients and chemotherapy in 103. Multivariate analysis was performed. Overall five-year survival was 75%. Median follow-up for surviving patients was 53 months. Actuarial five-year LR incidence was 13% in 200 patients with gross resection (R0+R1), it was 7% in R0 and 30% in R1 patients (p