Cannabidiol - Recent Advances

The aim of this review is to present some of the recent publications on cannabidiol (CBD; 2), a major non‐psychoactive constituent of Cannabis, and to give a general overview. Special emphasis is laid on biochemical and pharmacological advances, and on novel mechanisms recently put forward, to shed...

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Bibliographic Details
Published in:Chemistry & biodiversity 2007-08, Vol.4 (8), p.1678-1692
Main Authors: Mechoulam, Raphael, Peters, Maximilian, Murillo-Rodriguez, Eric, Hanuš, Lumír O.
Format: Article
Language:English
Subjects:
Animals
Antioxidants - chemical synthesis
Antioxidants - therapeutic use
Brain Ischemia - drug therapy
Cannabidiol
Cannabidiol - agonists
Cannabidiol - chemical synthesis
Cannabidiol - therapeutic use
Cannabinoid Receptor Antagonists
Cannabinoids
Cannabis
Humans
Marijuana
Neoplasms - drug therapy
Neuroprotective Agents - chemical synthesis
Neuroprotective Agents - therapeutic use
Receptor, Serotonin, 5-HT1A - drug effects
Receptors, Opioid - drug effects
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Summary:The aim of this review is to present some of the recent publications on cannabidiol (CBD; 2), a major non‐psychoactive constituent of Cannabis, and to give a general overview. Special emphasis is laid on biochemical and pharmacological advances, and on novel mechanisms recently put forward, to shed light on some of the pharmacological effects that can possibly be rationalized through these mechanisms. The plethora of positive pharmacological effects observed with CBD make this compound a highly attractive therapeutic entity.
ISSN:1612-1872
1612-1880
DOI:10.1002/cbdv.200790147