Multimodality Chamber for coregistered anatomical and molecular imaging of small animals

Modern imaging methods are applied extensively in translational animal research, and combined analysis of anatomical and functional imaging results is of increasing importance. Many imaging centers handle multiple independent animal colonies and use several imaging modalities, often in combination....

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Bibliographic Details
Published in:Lab animal 2007-09, Vol.36 (8), p.29-35
Main Authors: Bahadur, A.N, Wu, I.Q, Weinstein, D.M, Davis, M.D, Lewis, D.A, Kochunov, P, Keller, C
Format: Article
Language:English
Subjects:
Animal Models
Animals
Biomedical and Life Sciences
Cell migration
Diagnostic imaging
Disease Models, Animal
Female
image analysis
Image Interpretation, Computer-Assisted
Life Sciences
magnetic resonance imaging
Methods
Mice
Physiological aspects
Positron-Emission Tomography - instrumentation
Positron-Emission Tomography - methods
Rats
Rattus
resource
Software
Tomography, X-Ray Computed - instrumentation
Tomography, X-Ray Computed - methods
Veterinary Medicine/Veterinary Science
Veterinary physiology
Whole Body Imaging - instrumentation
Whole Body Imaging - methods
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Summary:Modern imaging methods are applied extensively in translational animal research, and combined analysis of anatomical and functional imaging results is of increasing importance. Many imaging centers handle multiple independent animal colonies and use several imaging modalities, often in combination. The authors have developed and successfully tested a two-piece acrylic Multimodality Chamber that enables investigators to coregister images from two or more modalities, including microMR, microCT, microPET and optical imaging.
ISSN:0093-7355
1548-4475
DOI:10.1038/laban0907-29