Lens cells: More than meets the eye

Lens cells originate from the head ectoderm and differentiate into an avascular organ constituted from two contiguous cell subpopulations of very different morphology. Lens cells, together with corneal cells, are responsible for the transmission and focusing of light onto the retina. Loss of transpa...

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Bibliographic Details
Published in:The international journal of biochemistry & cell biology 2007, Vol.39 (10), p.1754-1759
Main Authors: Tholozan, Frederique M.D., Quinlan, Roy A.
Format: Article
Language:English
Subjects:
Animals
Cataract
Cataract - etiology
Cataract - pathology
Cell Differentiation
Eye - cytology
Fibre cell differentiation
Humans
Lens
Lens, Crystalline - cytology
Lens, Crystalline - embryology
Lens, Crystalline - pathology
Lens, Crystalline - physiology
Models, Biological
PCO
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Summary:Lens cells originate from the head ectoderm and differentiate into an avascular organ constituted from two contiguous cell subpopulations of very different morphology. Lens cells, together with corneal cells, are responsible for the transmission and focusing of light onto the retina. Loss of transparency within the lens, via disruption of membrane transport or protein aggregation, results in cataract.
ISSN:1357-2725
1878-5875
DOI:10.1016/j.biocel.2007.06.021