Relationship of Hemoglobin A1C With the Presence and Severity of Retinopathy Upon Initial Screening of Type II Diabetes Mellitus

Purpose To determine a possible correlation specifically between hemoglobin A1C (HgbA1C) levels and the presence and severity of retinopathy during diabetic eye screening. Design Retrospective medical record review of all new patients examined in a Veteran Affairs Medical Center (VAMC) diabetic scre...

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Bibliographic Details
Published in:American journal of ophthalmology 2007-09, Vol.144 (3), p.456-457
Main Authors: Maa, April Y, Sullivan, Brian R
Format: Article
Language:English
Subjects:
Adult
Aged
Aged, 80 and over
Analysis of Variance
Biological and medical sciences
Comorbidity
Diabetes
Diabetes Mellitus, Type 2 - blood
Diabetic retinopathy
Diabetic Retinopathy - classification
Diabetic Retinopathy - diagnosis
Enzymes
Female
Glycated Hemoglobin A - analysis
Hemoglobin
Humans
Laboratories
Male
Medical sciences
Middle Aged
Miscellaneous
Ophthalmology
Retinopathies
Retrospective Studies
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Summary:Purpose To determine a possible correlation specifically between hemoglobin A1C (HgbA1C) levels and the presence and severity of retinopathy during diabetic eye screening. Design Retrospective medical record review of all new patients examined in a Veteran Affairs Medical Center (VAMC) diabetic screening clinic in 2005. Methods Six hundred and seven new patients were included in the study. Demographic data, HgbA1C levels, and grade of diabetic retinopathy were collected. The data analysis was performed via regression and analysis of variance (ANOVA). Results Among the 607 cases, no correlation between severity of retinopathy and HgbA1C level was found. A very small statistical difference of HgA1C levels existed between groups with and without retinopathy. Conclusion HgbA1C levels appeared to have little predictive value for presence/severity of retinopathy at initial screenings.
ISSN:0002-9394
1879-1891
DOI:10.1016/j.ajo.2007.04.008