Three new steroids from the roots of Serratula wolffii

Investigation of the methanol extract of the roots of Serratula wolffii resulted in an ecdysone-related compound, 2β,3β,20 R,22 R,25-pentahydroxy-5β-cholest-6,8(14)-dien ( 1), a new ecdysteroid, 24-methylene-shidasterone ( 2), the known compound stachysterone B ( 3) and its 14,15-α-epoxide ( 4), a n...

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Bibliographic Details
Published in:Steroids 2007-10, Vol.72 (11), p.751-755
Main Authors: Simon, András, Tóth, Gábor, Liktor-Busa, Erika, Kele, Zoltán, Takács, Mária, Gergely, András, Báthori, Mária
Format: Article
Language:English
Subjects:
14α,15α-epoxy-14,15-dihydrostachysterone B
24-Methylene-shidasterone
2β,3β,20 R,22 R,25-Pentahydroxy-5β-cholest-6,8-dien
Asteraceae - chemistry
Biological and medical sciences
Carbon Isotopes
Ecdysteroids
Fundamental and applied biological sciences. Psychology
Magnetic Resonance Spectroscopy
NMR
Phytosterols - chemistry
Phytosterols - isolation & purification
Plant Roots - chemistry
Protons
Serratula wolffii
Vertebrates: endocrinology
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Summary:Investigation of the methanol extract of the roots of Serratula wolffii resulted in an ecdysone-related compound, 2β,3β,20 R,22 R,25-pentahydroxy-5β-cholest-6,8(14)-dien ( 1), a new ecdysteroid, 24-methylene-shidasterone ( 2), the known compound stachysterone B ( 3) and its 14,15-α-epoxide ( 4), a novel natural product. The structures of compounds 1– 4 were established by spectral analysis ( 1H NMR, 13C NMR, COSY, NOESY, HMQC, HMQC-TOCSY and HMBC).
ISSN:0039-128X
1878-5867
DOI:10.1016/j.steroids.2007.06.004