Detection of patients with coronary artery disease using cardiac magnetic field mapping at rest

• Published in: Journal of electrocardiology 2007-09, Vol.40 (5), p.401-407
• Main Authors: Gapelyuk, Andrej, MSc, Wessel, Niels, PhD, Fischer, Robert, MD, Zacharzowsky, Udo, MD, Koch, Lydia, MD, Selbig, Daniela, MD, Schütt, Henry, MD, Sawitzki, Bianca, Luft, Friedrich C., MD, Dietz, Rainer, MD, Schirdewan, Alexander, MD
• Format: Article
• Language: English
• Subjects: Adult; Body Surface Potential Mapping - methods; Cardiac magnetic field mapping; Cardiovascular; Coronary artery disease; Coronary Artery Disease - diagnosis; Diagnosis, Computer-Assisted - methods; Female; Humans; Magnetics; Magnetocardiography - methods; Male; Middle Aged; Reproducibility of Results; Sensitivity and Specificity
• ISSN: 0022-0736; 1532-8430
• DOI: 10.1016/j.jelectrocard.2007.03.013

Abstract We studied the use of cardiac magnetic field mapping to detect patients with CAD without subjecting them to stress. Fifty-nine healthy control subjects and 101 patients with CAD without previous MI were included. The optimal positions for detecting CAD were located in the left superior parasternal and in the inferior midsternal area. Values for ST slope, ST shift, T peak amplitude, ST-T integral, and magnetic field map orientation differed significantly between the 2 groups. Three parameters together in a multivariate analysis yielded a sensitivity of 84% and a specificity of 83% in distinguishing patients with CAD from control subjects. We suggest that cardiac magnetic field mapping is a promising technique to identify patients with CAD.