Dual-Mode Nanoparticle Probes for High-Performance Magnetic Resonance and Fluorescence Imaging of Neuroblastoma

Working together: A “core–satellite” hybrid nanoparticle probe provides highly improved fluorescence and magnetic resonance (MR) imaging capabilities through synergistic enhancement of its respective components. These hybrid nanoprobes can be used for dual‐modal fluorescence and MR imaging of neurob...

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Bibliographic Details
Published in:Angewandte Chemie International Edition 2006-12, Vol.45 (48), p.8160-8162
Main Authors: Lee, Jae-Hyun, Jun, Young-wook, Yeon, Soo-In, Shin, Jeon-Soo, Cheon, Jinwoo
Format: Article
Language:English
Subjects:
Cell Line
colloids
diagnostic agents
Fluorescent Dyes - analysis
Fluorescent Dyes - chemistry
Humans
hybrid materials
Magnetic Resonance Imaging - methods
Molecular Probe Techniques
Nanoparticles - analysis
Nanoparticles - chemistry
Nanotechnology
Neuroblastoma - diagnosis
NMR imaging
Silicon Dioxide - chemistry
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Summary:Working together: A “core–satellite” hybrid nanoparticle probe provides highly improved fluorescence and magnetic resonance (MR) imaging capabilities through synergistic enhancement of its respective components. These hybrid nanoprobes can be used for dual‐modal fluorescence and MR imaging of neuroblastoma with expressed polysialic acids.
ISSN:1433-7851
1521-3773
DOI:10.1002/anie.200603052