Transoral laser microsurgery for untreated glottic carcinoma

To report the oncology and functional outcomes of transoral laser microsurgery (TLM) for untreated glottic carcinoma. A 2 center prospective case series analysis. Academic, tertiary referral centers. Seventy-six patients underwent TLM. Pathologic T stages were: T1, 45 (59%); T2, 21 (28%); T3, 5 (7%)...

Full description

Saved in:
Bibliographic Details
Published in:Otolaryngology-head and neck surgery 2007-09, Vol.137 (3), p.482-486
Main Authors: Grant, David G., Salassa, John R., Hinni, Michael L., Pearson, Bruce W., Hayden, Richard E., Perry, William C.
Format: Article
Language:English
Subjects:
Adult
Aged
Aged, 80 and over
Carcinoma, Squamous Cell - pathology
Carcinoma, Squamous Cell - surgery
Cohort Studies
Databases, Factual
Female
Glottis
Humans
Laryngeal Neoplasms - pathology
Laryngeal Neoplasms - surgery
Laser Therapy
Male
Microsurgery
Middle Aged
Mouth
Retrospective Studies
Treatment Outcome
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:To report the oncology and functional outcomes of transoral laser microsurgery (TLM) for untreated glottic carcinoma. A 2 center prospective case series analysis. Academic, tertiary referral centers. Seventy-six patients underwent TLM. Pathologic T stages were: T1, 45 (59%); T2, 21 (28%); T3, 5 (7%); and T4, 5 (7%). Five (7%) patients had neck dissections. Five (7%) patients received adjuvant radiotherapy. Mean follow-up was 42 months. Respective T1 and T2 5-year Kaplan-Meier estimates were: local control, 90% and 93%; loco-regional control, 90% and 93%; disease specific survival, 90% and 93%; and overall survival, 94% and 93%. The average hospital stay was 2 days. Two (3%) patients experienced major complications. The overall laryngeal preservation rate was 95% (72 of 76). TLM is a safe and effective treatment in select carcinoma of the glottic larynx. Low morbidity and mortality and short periods of hospitalization make TLM an attractive therapeutic option. TLM is an emerging strategy in the treatment of laryngeal cancer.
ISSN:0194-5998
1097-6817
DOI:10.1016/j.otohns.2007.05.064