Synthesis of 48 Disaccharide Building Blocks for the Assembly of a Heparin and Heparan Sulfate Oligosaccharide Library

An efficient synthesis of the entire set of suitably protected 48 disaccharide building blocks for the assembly of a heparin and heparan sulfate oligosaccharide library is described here.

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Bibliographic Details
Published in:Organic letters 2006-12, Vol.8 (26), p.5995-5998
Main Authors: Lu, Lung-Dai, Shie, Chi-Rung, Kulkarni, Suvarn S, Pan, Guan-Rong, Lu, Xin-An, Hung, Shang-Cheng
Format: Article
Language:English
Subjects:
Carbohydrate Sequence
Disaccharides - chemical synthesis
Heparin - chemistry
Heparitin Sulfate - chemistry
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Description
Summary:An efficient synthesis of the entire set of suitably protected 48 disaccharide building blocks for the assembly of a heparin and heparan sulfate oligosaccharide library is described here.
ISSN:1523-7060
1523-7052
DOI:10.1021/ol062464t