A Pressure-controlled Rat Ventilator With Electronically Preset Respirations

:  Major experimental surgery on laboratory animals requires adequate anesthesia and ventilation to keep the animal alive throughout the procedure. A ventilator is a machine that helps the anesthesized animal breathe through an endotracheal tube by pumping a volume of gas (oxygen, air, or other gase...

Full description

Saved in:
Bibliographic Details
Published in:Artificial organs 2006-12, Vol.30 (12), p.965-968
Main Authors: Ordodi, Valentin L., Paunescu, V., Mic, Ani A., Gabor, Lazar, Ionac, Mihai, Toma, Octavian, Sandesc, Dorel, Mic, Felix A.
Format: Article
Language:English
Subjects:
Anesthesia
Animals
Artificial
Equipment Design
Experimental
Lung
Monitoring, Physiologic - instrumentation
Pressure
Pulmonary Gas Exchange
Pulmonary Ventilation
Rat
Rats
Ventilator
Ventilators, Mechanical
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary::  Major experimental surgery on laboratory animals requires adequate anesthesia and ventilation to keep the animal alive throughout the procedure. A ventilator is a machine that helps the anesthesized animal breathe through an endotracheal tube by pumping a volume of gas (oxygen, air, or other gaseous mixtures), comparable with the normal tidal volume, into the animal's lungs. There are two main categories of ventilators for small laboratory rodents: volume‐controlled and pressure‐controlled ones. The volume‐controlled ventilator injects a preset volume into the animal's lungs, no matter the airways' resistance (with the peak inspiratory pressure allowed to vary), while the pressure ventilator controls the inspiratory pressure and allows the inspiratory volume to vary. Here we show a rat pressure ventilator with a simple expiratory valve that allows gas delivery through electronic expiration control and offers easy pressure monitoring and frequency change during ventilation.
ISSN:0160-564X
1525-1594
DOI:10.1111/j.1525-1594.2006.00329.x