Molecular study of genes involved in virulence regulatory pathways in Bacillus anthracis vaccine strain "Carbosap"

This study investigated the genetic bases of attenuation in the Bacillus anthracis vaccine strain "Carbosap" used in Italy against anthrax in cattle and sheep. Twelve genes involved in virulence regulatory pathways underwent sequence analysis in comparison with a B. anthracis virulent stra...

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Bibliographic Details
Published in:The New microbiologica 2006-10, Vol.29 (4), p.307-310
Main Authors: La Rosa, Giuseppina, Muscillo, Michele, Sali, Michela, De Carolis, Elena, Marianelli, Cinzia, Ciuchini, Franco, Fasanella, Antonio, Adone, Rosanna
Format: Article
Language:English
Subjects:
Animals
Anthrax - microbiology
Anthrax - prevention & control
Anthrax - veterinary
Anthrax Vaccines
Bacillus anthracis
Bacillus anthracis - classification
Bacillus anthracis - genetics
Bacillus anthracis - immunology
Bacillus anthracis - pathogenicity
Bacterial Proteins - genetics
Cattle
Gene Expression Regulation, Bacterial
Italy
Polymerase Chain Reaction - methods
Sequence Analysis, DNA
Sheep
Vaccines, Attenuated
Virulence
Virulence Factors - genetics
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Summary:This study investigated the genetic bases of attenuation in the Bacillus anthracis vaccine strain "Carbosap" used in Italy against anthrax in cattle and sheep. Twelve genes involved in virulence regulatory pathways underwent sequence analysis in comparison with a B. anthracis virulent strain.
ISSN:1121-7138