Tolerance and efficacy of an air-filled balloon in non-morbidly obese patients: results of a prospective multicenter study

Intragastric balloons have been proposed to induce body weight loss in obese subjects. Most studies were performed using liquid-filled balloons. Air-filled balloons may increase digestive tolerance. Our goal was to study the tolerance and efficacy of a new air-filled intragastric balloon in nonmorbi...

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Published in:Obesity surgery 2007-06, Vol.17 (6), p.764-769
Main Authors: Mion, François, Gincul, Rodica, Roman, Sabine, Beorchia, Sylvain, Hedelius, Frank, Claudel, Nicolas, Bory, Roger-Michel, Malvoisin, Etienne, Trepo, Frédérique, Napoleon, Bertrand
Format: Article
Language:English
Subjects:
Adolescent
Adult
Air
Equipment Design
Female
Follow-Up Studies
Gastric Balloon
Gastrointestinal surgery
Humans
Male
Middle Aged
Obesity
Obesity - therapy
Prospective Studies
Treatment Outcome
Weight control
Weight Loss
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cited_by cdi_FETCH-LOGICAL-c326t-a096b01088fe129cdd10e79a9f3b13bd48e4dd472fd8d406998df0574c65995e3
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container_title Obesity surgery
container_volume 17
creator Mion, François
Gincul, Rodica
Roman, Sabine
Beorchia, Sylvain
Hedelius, Frank
Claudel, Nicolas
Bory, Roger-Michel
Malvoisin, Etienne
Trepo, Frédérique
Napoleon, Bertrand
description Intragastric balloons have been proposed to induce body weight loss in obese subjects. Most studies were performed using liquid-filled balloons. Air-filled balloons may increase digestive tolerance. Our goal was to study the tolerance and efficacy of a new air-filled intragastric balloon in nonmorbidly obese patients. 32 patients were included, with a mean BMI of 35.0 (range 30.1-40.0). The balloon was inserted under general anaesthesia, inflated with 800 ml of air, and removed 4 months later. Tolerance and body weight were monitored until 12 months after removal. Ghrelin levels were measured before balloon insertion, 1 and 4 weeks after, and before removal. Weight loss was significant at 1, 2 and 4 months after balloon insertion (6, 7 and 10 kg, respectively, P10%, and satisfaction with the method was 87% for these 9 patients, and 22% for the other patients who had weight loss
doi_str_mv 10.1007/s11695-007-9141-z
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Early removal of the balloon occurred in 3 cases. 28 patients were contacted 12 months after balloon removal: 2 had undergone gastric banding; among the 26 remaining, the mean weight loss was 7 kg. 9 patients (30%) remained with a weight loss &gt;10%, and satisfaction with the method was 87% for these 9 patients, and 22% for the other patients who had weight loss &lt;10% (P&lt;0.04). Fasting plasma ghrelin levels increased at week 1 and 4 after balloon insertion, and decreased at week 16 (P&lt;0.001). CONCLUSIONS. The air-filled intragastric balloon was safe. 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subjects Adolescent
Adult
Air
Equipment Design
Female
Follow-Up Studies
Gastric Balloon
Gastrointestinal surgery
Humans
Male
Middle Aged
Obesity
Obesity - therapy
Prospective Studies
Treatment Outcome
Weight control
Weight Loss
title Tolerance and efficacy of an air-filled balloon in non-morbidly obese patients: results of a prospective multicenter study
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