Palivizumab Treatment of Respiratory Syncytial Virus Infection after Allogeneic Hematopoietic Stem Cell Transplantation

Among 40 allogeneic stem cell transplant recipients who developed symptomatic respiratory syncytial virus infection, including 22 patients with lower respiratory tract infection, 19 received palivizumab (9 of whom had upper respiratory tract disease). Palivizumab did not prevent progression to lower...

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Published in:Clinical infectious diseases 2007-10, Vol.45 (8), p.1019-1024
Main Authors: de Fontbrune, Flore Sicre, Robin, Marie, Porcher, Raphael, Scieux, Catherine, de Latour, Régis Peffault, Ferry, Christèle, Rocha, Vanderson, Boudjedir, Karim, Devergie, Agnès, Bergeron, Anne, Gluckman, Eliane, Azoulay, Elie, Lapalu, Jordane, Socié, Gérard, Ribaud, Patricia
Format: Article
Language:English
Subjects:
Adolescent
Adult
Aged
Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy
Antibodies, Monoclonal - therapeutic use
Antibodies, Monoclonal, Humanized
Antiviral Agents - therapeutic use
Biological and medical sciences
Blood donation
Bone marrow
Bone marrow, stem cells transplantation. Graft versus host reaction
Brief Reports
Child
Child, Preschool
Cord blood
Hematologic Diseases - complications
Hematopoietic Stem Cell Transplantation
Human respiratory syncytial virus
Human viral diseases
Humans
Immunomodulators
Infections
Infectious diseases
Medical sciences
Middle Aged
Monoclonal antibodies
Mortality
Palivizumab
Pharmacology. Drug treatments
Pneumonia - drug therapy
Pneumonia - virology
Respiratory diseases
Respiratory syncytial virus
Respiratory syncytial virus infections
Respiratory Syncytial Virus Infections - drug therapy
Respiratory syncytial viruses
Respiratory tract infections
Respiratory Tract Infections - drug therapy
Respiratory Tract Infections - virology
Retrospective Studies
Stem cells
Survival Analysis
Transfusions. Complications. Transfusion reactions. Cell and gene therapy
Transplants & implants
Viral diseases
Viral diseases of the respiratory system and ent viral diseases
Viruses
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creator de Fontbrune, Flore Sicre
Robin, Marie
Porcher, Raphael
Scieux, Catherine
de Latour, Régis Peffault
Ferry, Christèle
Rocha, Vanderson
Boudjedir, Karim
Devergie, Agnès
Bergeron, Anne
Gluckman, Eliane
Azoulay, Elie
Lapalu, Jordane
Socié, Gérard
Ribaud, Patricia
description Among 40 allogeneic stem cell transplant recipients who developed symptomatic respiratory syncytial virus infection, including 22 patients with lower respiratory tract infection, 19 received palivizumab (9 of whom had upper respiratory tract disease). Palivizumab did not prevent progression to lower respiratory infection and had no impact on the overall survival rate.
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Graft versus host reaction ; Brief Reports ; Child ; Child, Preschool ; Cord blood ; Hematologic Diseases - complications ; Hematopoietic Stem Cell Transplantation ; Human respiratory syncytial virus ; Human viral diseases ; Humans ; Immunomodulators ; Infections ; Infectious diseases ; Medical sciences ; Middle Aged ; Monoclonal antibodies ; Mortality ; Palivizumab ; Pharmacology. Drug treatments ; Pneumonia - drug therapy ; Pneumonia - virology ; Respiratory diseases ; Respiratory syncytial virus ; Respiratory syncytial virus infections ; Respiratory Syncytial Virus Infections - drug therapy ; Respiratory syncytial viruses ; Respiratory tract infections ; Respiratory Tract Infections - drug therapy ; Respiratory Tract Infections - virology ; Retrospective Studies ; Stem cells ; Survival Analysis ; Transfusions. Complications. Transfusion reactions. 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subjects Adolescent
Adult
Aged
Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy
Antibodies, Monoclonal - therapeutic use
Antibodies, Monoclonal, Humanized
Antiviral Agents - therapeutic use
Biological and medical sciences
Blood donation
Bone marrow
Bone marrow, stem cells transplantation. Graft versus host reaction
Brief Reports
Child
Child, Preschool
Cord blood
Hematologic Diseases - complications
Hematopoietic Stem Cell Transplantation
Human respiratory syncytial virus
Human viral diseases
Humans
Immunomodulators
Infections
Infectious diseases
Medical sciences
Middle Aged
Monoclonal antibodies
Mortality
Palivizumab
Pharmacology. Drug treatments
Pneumonia - drug therapy
Pneumonia - virology
Respiratory diseases
Respiratory syncytial virus
Respiratory syncytial virus infections
Respiratory Syncytial Virus Infections - drug therapy
Respiratory syncytial viruses
Respiratory tract infections
Respiratory Tract Infections - drug therapy
Respiratory Tract Infections - virology
Retrospective Studies
Stem cells
Survival Analysis
Transfusions. Complications. Transfusion reactions. Cell and gene therapy
Transplants & implants
Viral diseases
Viral diseases of the respiratory system and ent viral diseases
Viruses
title Palivizumab Treatment of Respiratory Syncytial Virus Infection after Allogeneic Hematopoietic Stem Cell Transplantation
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