Presence of Carotid and Peripheral Arterial Disease in Patients With Left Main Disease

• Published in: The American journal of cardiology 2007-10, Vol.100 (7), p.1087-1089
• Main Authors: Doonan, Aaron L., MD, Karha, Juhana, MD, Carrigan, Thomas P., MD, Bavry, Anthony A., MD, MPH, Begelman, Susan M., MD, Ellis, Stephen G., MD, Yadav, Jay, MD, Bhatt, Deepak L., MD
• Format: Article
• Language: English
• Subjects: Biological and medical sciences; Blood and lymphatic vessels; Cardiology; Cardiology. Vascular system; Cardiovascular; Cardiovascular disease; Carotid Artery Diseases - complications; Carotid Artery Diseases - diagnostic imaging; Carotid Artery Diseases - epidemiology; Carotid Stenosis - diagnostic imaging; Carotid Stenosis - epidemiology; Carotid Stenosis - etiology; Coronary Angiography; Coronary Artery Disease - complications; Coronary Artery Disease - diagnostic imaging; Coronary Artery Disease - epidemiology; Coronary Stenosis - diagnostic imaging; Coronary Stenosis - epidemiology; Coronary Stenosis - etiology; Coronary vessels; Diseases of the peripheral vessels. Diseases of the vena cava. Miscellaneous; Female; Heart surgery; Humans; Male; Medical imaging; Medical sciences; Peripheral Vascular Diseases - complications; Peripheral Vascular Diseases - diagnosis; Peripheral Vascular Diseases - epidemiology; Ultrasonography
• ISSN: 0002-9149; 1879-1913
• DOI: 10.1016/j.amjcard.2007.05.031

Left main (LM) coronary disease, carotid artery disease, and peripheral arterial disease each reflects advanced atherosclerosis. The frequency of their coexistence in the same patient has not been fully elucidated. All coronary angiograms obtained at the Cleveland Clinic from November 2003 to October 2005 were analyzed for presence of LM stenosis ≥50%. Patients with previous coronary artery bypass graft surgery were excluded. Patients with available carotid ultrasound and ankle-brachial indexes formed the analysis cohorts. A total of 10,298 coronary angiograms were obtained in 9,715 patients. There were 186 patients with LM disease and 1,913 patients without LM disease with carotid artery ultrasound data. There were 29 patients with LM disease and 604 patients without LM disease with available ankle-brachial indexes. Patients with significant LM disease more frequently had associated carotid stenosis ≥60% compared with patients without LM disease (31.2% vs 15.2%, p