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Presence of Carotid and Peripheral Arterial Disease in Patients With Left Main Disease
Left main (LM) coronary disease, carotid artery disease, and peripheral arterial disease each reflects advanced atherosclerosis. The frequency of their coexistence in the same patient has not been fully elucidated. All coronary angiograms obtained at the Cleveland Clinic from November 2003 to Octobe...
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| Published in: | The American journal of cardiology 2007-10, Vol.100 (7), p.1087-1089 |
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| container_end_page | 1089 |
| container_issue | 7 |
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| container_title | The American journal of cardiology |
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| creator | Doonan, Aaron L., MD Karha, Juhana, MD Carrigan, Thomas P., MD Bavry, Anthony A., MD, MPH Begelman, Susan M., MD Ellis, Stephen G., MD Yadav, Jay, MD Bhatt, Deepak L., MD |
| description | Left main (LM) coronary disease, carotid artery disease, and peripheral arterial disease each reflects advanced atherosclerosis. The frequency of their coexistence in the same patient has not been fully elucidated. All coronary angiograms obtained at the Cleveland Clinic from November 2003 to October 2005 were analyzed for presence of LM stenosis ≥50%. Patients with previous coronary artery bypass graft surgery were excluded. Patients with available carotid ultrasound and ankle-brachial indexes formed the analysis cohorts. A total of 10,298 coronary angiograms were obtained in 9,715 patients. There were 186 patients with LM disease and 1,913 patients without LM disease with carotid artery ultrasound data. There were 29 patients with LM disease and 604 patients without LM disease with available ankle-brachial indexes. Patients with significant LM disease more frequently had associated carotid stenosis ≥60% compared with patients without LM disease (31.2% vs 15.2%, p |
| doi_str_mv | 10.1016/j.amjcard.2007.05.031 |
| format | article |
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The frequency of their coexistence in the same patient has not been fully elucidated. All coronary angiograms obtained at the Cleveland Clinic from November 2003 to October 2005 were analyzed for presence of LM stenosis ≥50%. Patients with previous coronary artery bypass graft surgery were excluded. Patients with available carotid ultrasound and ankle-brachial indexes formed the analysis cohorts. A total of 10,298 coronary angiograms were obtained in 9,715 patients. There were 186 patients with LM disease and 1,913 patients without LM disease with carotid artery ultrasound data. There were 29 patients with LM disease and 604 patients without LM disease with available ankle-brachial indexes. Patients with significant LM disease more frequently had associated carotid stenosis ≥60% compared with patients without LM disease (31.2% vs 15.2%, p <0.0001). Patients with LM disease had lower mean ankle-brachial indexes compared with patients without LM disease (0.78 vs 0.87, p = 0.042). In conclusion, compared with patients without LM disease, patients with LM disease have a higher burden of advanced atherosclerosis as evidenced by a higher prevalence of significant carotid stenosis and lower ankle-brachial indexes.</description><identifier>ISSN: 0002-9149</identifier><identifier>EISSN: 1879-1913</identifier><identifier>DOI: 10.1016/j.amjcard.2007.05.031</identifier><identifier>PMID: 17884367</identifier><identifier>CODEN: AJCDAG</identifier><language>eng</language><publisher>New York, NY: Elsevier Inc</publisher><subject>Biological and medical sciences ; Blood and lymphatic vessels ; Cardiology ; Cardiology. Vascular system ; Cardiovascular ; Cardiovascular disease ; Carotid Artery Diseases - complications ; Carotid Artery Diseases - diagnostic imaging ; Carotid Artery Diseases - epidemiology ; Carotid Stenosis - diagnostic imaging ; Carotid Stenosis - epidemiology ; Carotid Stenosis - etiology ; Coronary Angiography ; Coronary Artery Disease - complications ; Coronary Artery Disease - diagnostic imaging ; Coronary Artery Disease - epidemiology ; Coronary Stenosis - diagnostic imaging ; Coronary Stenosis - epidemiology ; Coronary Stenosis - etiology ; Coronary vessels ; Diseases of the peripheral vessels. Diseases of the vena cava. Miscellaneous ; Female ; Heart surgery ; Humans ; Male ; Medical imaging ; Medical sciences ; Peripheral Vascular Diseases - complications ; Peripheral Vascular Diseases - diagnosis ; Peripheral Vascular Diseases - epidemiology ; Ultrasonography</subject><ispartof>The American journal of cardiology, 2007-10, Vol.100 (7), p.1087-1089</ispartof><rights>Elsevier Inc.</rights><rights>2007 Elsevier Inc.</rights><rights>2007 INIST-CNRS</rights><rights>Copyright Elsevier Sequoia S.A. Oct 1, 2007</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c475t-6126b130be6b2694375c529619bfbb03c69058847d37ce79d97b8b7c8315ee503</citedby><cites>FETCH-LOGICAL-c475t-6126b130be6b2694375c529619bfbb03c69058847d37ce79d97b8b7c8315ee503</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,27924,27925</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=19142408$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/17884367$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Doonan, Aaron L., MD</creatorcontrib><creatorcontrib>Karha, Juhana, MD</creatorcontrib><creatorcontrib>Carrigan, Thomas P., MD</creatorcontrib><creatorcontrib>Bavry, Anthony A., MD, MPH</creatorcontrib><creatorcontrib>Begelman, Susan M., MD</creatorcontrib><creatorcontrib>Ellis, Stephen G., MD</creatorcontrib><creatorcontrib>Yadav, Jay, MD</creatorcontrib><creatorcontrib>Bhatt, Deepak L., MD</creatorcontrib><title>Presence of Carotid and Peripheral Arterial Disease in Patients With Left Main Disease</title><title>The American journal of cardiology</title><addtitle>Am J Cardiol</addtitle><description>Left main (LM) coronary disease, carotid artery disease, and peripheral arterial disease each reflects advanced atherosclerosis. The frequency of their coexistence in the same patient has not been fully elucidated. All coronary angiograms obtained at the Cleveland Clinic from November 2003 to October 2005 were analyzed for presence of LM stenosis ≥50%. Patients with previous coronary artery bypass graft surgery were excluded. Patients with available carotid ultrasound and ankle-brachial indexes formed the analysis cohorts. A total of 10,298 coronary angiograms were obtained in 9,715 patients. There were 186 patients with LM disease and 1,913 patients without LM disease with carotid artery ultrasound data. There were 29 patients with LM disease and 604 patients without LM disease with available ankle-brachial indexes. Patients with significant LM disease more frequently had associated carotid stenosis ≥60% compared with patients without LM disease (31.2% vs 15.2%, p <0.0001). Patients with LM disease had lower mean ankle-brachial indexes compared with patients without LM disease (0.78 vs 0.87, p = 0.042). In conclusion, compared with patients without LM disease, patients with LM disease have a higher burden of advanced atherosclerosis as evidenced by a higher prevalence of significant carotid stenosis and lower ankle-brachial indexes.</description><subject>Biological and medical sciences</subject><subject>Blood and lymphatic vessels</subject><subject>Cardiology</subject><subject>Cardiology. Vascular system</subject><subject>Cardiovascular</subject><subject>Cardiovascular disease</subject><subject>Carotid Artery Diseases - complications</subject><subject>Carotid Artery Diseases - diagnostic imaging</subject><subject>Carotid Artery Diseases - epidemiology</subject><subject>Carotid Stenosis - diagnostic imaging</subject><subject>Carotid Stenosis - epidemiology</subject><subject>Carotid Stenosis - etiology</subject><subject>Coronary Angiography</subject><subject>Coronary Artery Disease - complications</subject><subject>Coronary Artery Disease - diagnostic imaging</subject><subject>Coronary Artery Disease - epidemiology</subject><subject>Coronary Stenosis - diagnostic imaging</subject><subject>Coronary Stenosis - epidemiology</subject><subject>Coronary Stenosis - etiology</subject><subject>Coronary vessels</subject><subject>Diseases of the peripheral vessels. Diseases of the vena cava. Miscellaneous</subject><subject>Female</subject><subject>Heart surgery</subject><subject>Humans</subject><subject>Male</subject><subject>Medical imaging</subject><subject>Medical sciences</subject><subject>Peripheral Vascular Diseases - complications</subject><subject>Peripheral Vascular Diseases - diagnosis</subject><subject>Peripheral Vascular Diseases - epidemiology</subject><subject>Ultrasonography</subject><issn>0002-9149</issn><issn>1879-1913</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2007</creationdate><recordtype>article</recordtype><recordid>eNqFklur1DAQx4sonvXoR1CCoG-tM02TNC_KYb3CigveHkOaTjmp3XZNusL59qZs8cB58Wkyw28u-c9k2VOEAgHlq76wh97Z0BYlgCpAFMDxXrbBWukcNfL72QYAylxjpS-yRzH2yUUU8mF2gaquKy7VJvuxDxRpdMSmjm1tmGbfMju2bE_BH68p2IFdhTk56fHWR7KRmB_Z3s6exjmyn36-ZjvqZvbZpviKPM4edHaI9GS1l9n39---bT_muy8fPm2vdrmrlJhziaVskENDsimlrrgSTpRaom66pgHupAaRRlUtV46UbrVq6ka5mqMgEsAvs5fnuscw_T5RnM3BR0fDYEeaTtHImgMIuYDP74D9dApjms2UHHjqjZggcYZcmGIM1Jlj8AcbbgyCWVQ3vVlVN4vqBoRJqqe8Z2vxU3Og9jZrlTkBL1bARmeHLtjR-XjLpR2VFdSJe3PmKGn2x1Mw0fllO60P5GbTTv6_o7y-U8ENfvSp6S-6ofjv02hiacB8XU5kuRBQgGUy_C9BoLTU</recordid><startdate>20071001</startdate><enddate>20071001</enddate><creator>Doonan, Aaron L., MD</creator><creator>Karha, Juhana, MD</creator><creator>Carrigan, Thomas P., MD</creator><creator>Bavry, Anthony A., MD, MPH</creator><creator>Begelman, Susan M., MD</creator><creator>Ellis, Stephen G., MD</creator><creator>Yadav, Jay, MD</creator><creator>Bhatt, Deepak L., MD</creator><general>Elsevier Inc</general><general>Elsevier</general><general>Elsevier Limited</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7TS</scope><scope>8FD</scope><scope>FR3</scope><scope>K9.</scope><scope>M7Z</scope><scope>NAPCQ</scope><scope>P64</scope><scope>7X8</scope></search><sort><creationdate>20071001</creationdate><title>Presence of Carotid and Peripheral Arterial Disease in Patients With Left Main Disease</title><author>Doonan, Aaron L., MD ; Karha, Juhana, MD ; Carrigan, Thomas P., MD ; Bavry, Anthony A., MD, MPH ; Begelman, Susan M., MD ; Ellis, Stephen G., MD ; Yadav, Jay, MD ; Bhatt, Deepak L., MD</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c475t-6126b130be6b2694375c529619bfbb03c69058847d37ce79d97b8b7c8315ee503</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2007</creationdate><topic>Biological and medical sciences</topic><topic>Blood and lymphatic vessels</topic><topic>Cardiology</topic><topic>Cardiology. Vascular system</topic><topic>Cardiovascular</topic><topic>Cardiovascular disease</topic><topic>Carotid Artery Diseases - complications</topic><topic>Carotid Artery Diseases - diagnostic imaging</topic><topic>Carotid Artery Diseases - epidemiology</topic><topic>Carotid Stenosis - diagnostic imaging</topic><topic>Carotid Stenosis - epidemiology</topic><topic>Carotid Stenosis - etiology</topic><topic>Coronary Angiography</topic><topic>Coronary Artery Disease - complications</topic><topic>Coronary Artery Disease - diagnostic imaging</topic><topic>Coronary Artery Disease - epidemiology</topic><topic>Coronary Stenosis - diagnostic imaging</topic><topic>Coronary Stenosis - epidemiology</topic><topic>Coronary Stenosis - etiology</topic><topic>Coronary vessels</topic><topic>Diseases of the peripheral vessels. Diseases of the vena cava. Miscellaneous</topic><topic>Female</topic><topic>Heart surgery</topic><topic>Humans</topic><topic>Male</topic><topic>Medical imaging</topic><topic>Medical sciences</topic><topic>Peripheral Vascular Diseases - complications</topic><topic>Peripheral Vascular Diseases - diagnosis</topic><topic>Peripheral Vascular Diseases - epidemiology</topic><topic>Ultrasonography</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Doonan, Aaron L., MD</creatorcontrib><creatorcontrib>Karha, Juhana, MD</creatorcontrib><creatorcontrib>Carrigan, Thomas P., MD</creatorcontrib><creatorcontrib>Bavry, Anthony A., MD, MPH</creatorcontrib><creatorcontrib>Begelman, Susan M., MD</creatorcontrib><creatorcontrib>Ellis, Stephen G., MD</creatorcontrib><creatorcontrib>Yadav, Jay, MD</creatorcontrib><creatorcontrib>Bhatt, Deepak L., MD</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Physical Education Index</collection><collection>Technology Research Database</collection><collection>Engineering Research Database</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Biochemistry Abstracts 1</collection><collection>Nursing & Allied Health Premium</collection><collection>Biotechnology and BioEngineering Abstracts</collection><collection>MEDLINE - Academic</collection><jtitle>The American journal of cardiology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Doonan, Aaron L., MD</au><au>Karha, Juhana, MD</au><au>Carrigan, Thomas P., MD</au><au>Bavry, Anthony A., MD, MPH</au><au>Begelman, Susan M., MD</au><au>Ellis, Stephen G., MD</au><au>Yadav, Jay, MD</au><au>Bhatt, Deepak L., MD</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Presence of Carotid and Peripheral Arterial Disease in Patients With Left Main Disease</atitle><jtitle>The American journal of cardiology</jtitle><addtitle>Am J Cardiol</addtitle><date>2007-10-01</date><risdate>2007</risdate><volume>100</volume><issue>7</issue><spage>1087</spage><epage>1089</epage><pages>1087-1089</pages><issn>0002-9149</issn><eissn>1879-1913</eissn><coden>AJCDAG</coden><abstract>Left main (LM) coronary disease, carotid artery disease, and peripheral arterial disease each reflects advanced atherosclerosis. The frequency of their coexistence in the same patient has not been fully elucidated. All coronary angiograms obtained at the Cleveland Clinic from November 2003 to October 2005 were analyzed for presence of LM stenosis ≥50%. Patients with previous coronary artery bypass graft surgery were excluded. Patients with available carotid ultrasound and ankle-brachial indexes formed the analysis cohorts. A total of 10,298 coronary angiograms were obtained in 9,715 patients. There were 186 patients with LM disease and 1,913 patients without LM disease with carotid artery ultrasound data. There were 29 patients with LM disease and 604 patients without LM disease with available ankle-brachial indexes. Patients with significant LM disease more frequently had associated carotid stenosis ≥60% compared with patients without LM disease (31.2% vs 15.2%, p <0.0001). Patients with LM disease had lower mean ankle-brachial indexes compared with patients without LM disease (0.78 vs 0.87, p = 0.042). In conclusion, compared with patients without LM disease, patients with LM disease have a higher burden of advanced atherosclerosis as evidenced by a higher prevalence of significant carotid stenosis and lower ankle-brachial indexes.</abstract><cop>New York, NY</cop><pub>Elsevier Inc</pub><pmid>17884367</pmid><doi>10.1016/j.amjcard.2007.05.031</doi><tpages>3</tpages></addata></record> |
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| subjects | Biological and medical sciences Blood and lymphatic vessels Cardiology Cardiology. Vascular system Cardiovascular Cardiovascular disease Carotid Artery Diseases - complications Carotid Artery Diseases - diagnostic imaging Carotid Artery Diseases - epidemiology Carotid Stenosis - diagnostic imaging Carotid Stenosis - epidemiology Carotid Stenosis - etiology Coronary Angiography Coronary Artery Disease - complications Coronary Artery Disease - diagnostic imaging Coronary Artery Disease - epidemiology Coronary Stenosis - diagnostic imaging Coronary Stenosis - epidemiology Coronary Stenosis - etiology Coronary vessels Diseases of the peripheral vessels. Diseases of the vena cava. Miscellaneous Female Heart surgery Humans Male Medical imaging Medical sciences Peripheral Vascular Diseases - complications Peripheral Vascular Diseases - diagnosis Peripheral Vascular Diseases - epidemiology Ultrasonography |
| title | Presence of Carotid and Peripheral Arterial Disease in Patients With Left Main Disease |
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