Comparing the moisturizing effects of ascorbic acid and calcium ascorbate against that of tocopherol in emulsions

Calcium ascorbate (CAAS), which is a hydrophilic and stable derivative of ascorbic acid (vitamin C) (AA), is commonly used in foods as an antioxidative agent. There are very limited reports on its dermatological use in the literature. In this paper, it is reported that CAAS could be used in place of...

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Bibliographic Details
Published in:Journal of cosmetic science 2006-11, Vol.57 (6), p.465-473
Main Authors: GONULLU, U, SENSOY, D, UNER, M, YENER, G, ALTINKURT, T
Format: Article
Language:English
Subjects:
Adult
Antioxidants - pharmacology
Applied sciences
Ascorbic Acid - administration & dosage
Ascorbic Acid - pharmacology
Biological and medical sciences
Calcium Compounds - administration & dosage
Calcium Compounds - chemistry
Calcium Compounds - pharmacology
Chemical industry and chemicals
Cosmetics - administration & dosage
Cosmetics - chemical synthesis
Cosmetics - pharmacology
Cosmetics, toiletries
Diseases of the skin. Cosmetics
Emulsions - administration & dosage
Emulsions - chemical synthesis
Emulsions - pharmacology
Exact sciences and technology
Female
Galvanic Skin Response - drug effects
Humans
Medical sciences
Radiotherapy. Instrumental treatment. Physiotherapy. Reeducation. Rehabilitation, orthophony, crenotherapy. Diet therapy and various other treatments (general aspects)
Skin Care - methods
Tocopherols - pharmacology
Washing products. Cosmetics and toiletries. Perfumes
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Summary:Calcium ascorbate (CAAS), which is a hydrophilic and stable derivative of ascorbic acid (vitamin C) (AA), is commonly used in foods as an antioxidative agent. There are very limited reports on its dermatological use in the literature. In this paper, it is reported that CAAS could be used in place of ascorbic acid, which has chemical stability problems in topicals due to degradation by oxidation. The aim of this study was to investigate the skin-hydrating effect of CAAS compared to those of ascorbic acid and tocopherol (vitamin E) (T), which is a potential skin moisturizer and commonly used in dermocosmetics. Vitamins are incorporated into two kinds of base creams (o/w and w/o emulsion creams), alone and in combinations. Formulations were applied to the inner forearms of volunteers, and skin conductance was measured by using a corneometer. Data obtained were statistically evaluated. It was found that the skin-hydrating effect of CAAS was higher than that of AA and lower than that of T. However, its effect was very close to that of T.
ISSN:1525-7886
2689-5153