Association between ulcerative colitis and multiple sclerosis

An association between inflammatory bowel disease (IBD) and multiple sclerosis (MS) has been described. The current study was undertaken to explore this association further. Personal records of patients with IBD and MS were reviewed. In addition, a search of medical records at a large tertiary teach...

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Bibliographic Details
Published in:Internal medicine journal 2007-10, Vol.37 (10), p.721-724
Main Authors: Pokorny, C. S., Beran, R. G., Pokorny, M. J.
Format: Article
Language:English
Subjects:
Adult
Aged
anti-tumour necrosis factor
Colitis, Ulcerative - complications
Colitis, Ulcerative - diagnosis
Crohn's disease
Female
Humans
Male
multiple sclerosis
Multiple Sclerosis - complications
Multiple Sclerosis - diagnosis
Retrospective Studies
ulcerative colitis
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Summary:An association between inflammatory bowel disease (IBD) and multiple sclerosis (MS) has been described. The current study was undertaken to explore this association further. Personal records of patients with IBD and MS were reviewed. In addition, a search of medical records at a large tertiary teaching hospital in Sydney was carried out for the years 1996–2006. Four patients (three women and one man) with both ulcerative colitis and MS were identified. MS did not occur in any of our patients with Crohn’s disease. The association between ulcerative colitis and MS appears to be real and may help identify common factors involved in the cause of these two diseases. No association was found in this study between MS and Crohn’s disease, sparking consideration why such difference should occur. With the increasing use of biological therapies in IBD and their reported propensity to cause demyelination, recognition of an association is all the more important.
ISSN:1444-0903
1445-5994
DOI:10.1111/j.1445-5994.2007.01452.x