Correction of Celiac Disease After Allogeneic Hematopoietic Stem Cell Transplantation for Acute Myelogenous Leukemia

Allogeneic hematopoietic stem cell transplantation has been shown to correct or improve a variety of autoimmune disorders. This has not been reported for celiac disease, but transmission to a hematopoietic stem cell transplantation recipient from a donor with celiac disease has been reported. We rep...

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Bibliographic Details
Published in:Pediatrics (Evanston) 2007-10, Vol.120 (4), p.e1120-e1122
Main Authors: Kline, Ronald M, Neudorf, Steven M.L, Baron, Howard I
Format: Article
Language:English
Subjects:
Celiac disease
Celiac Disease - complications
Celiac Disease - therapy
Child
Children & youth
Female
Hematopoietic Stem Cell Transplantation
Humans
Leukemia
Leukemia, Myeloid, Acute - complications
Leukemia, Myeloid, Acute - therapy
Pediatrics
Siblings
Stem cells
Transplantation, Homologous
Transplants & implants
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Description
Summary:Allogeneic hematopoietic stem cell transplantation has been shown to correct or improve a variety of autoimmune disorders. This has not been reported for celiac disease, but transmission to a hematopoietic stem cell transplantation recipient from a donor with celiac disease has been reported. We report a 12-year-old girl with celiac disease who was diagnosed with acute leukemia and received an allogeneic hematopoietic stem cell transplant. Her celiac disease resolved after the hematopoietic stem cell transplant.
ISSN:0031-4005
1098-4275
DOI:10.1542/peds.2006-3397