Distribution of a 9.1-kb Insertion-Deletion Polymorphism Among Native and Admixed Populations from Argentina

• Published in: Human biology 2006-12, Vol.78 (6), p.743-748
• Main Authors: Demarchi, Darío A., García, Angelina, Altuna, María Eugenia
• Format: Article
• Language: English
• Subjects: Alleles; AMERINDIANS; ARGENTINA; Biological anthropology; Brief Communications; Chromosomes, Human, Pair 22 - genetics; Data analysis; DNA; Equilibrium; European Continental Ancestry Group - genetics; Gene Deletion; Gene Frequency; Genetic diversity; Genetic equilibrium; Genetic polymorphisms; GENETIC VARIATION; Genetics, Population; Genotype; Genotypes; Human biology; Human genetics; Humans; Indians, South American - genetics; Indians, South American - statistics & numerical data; Indigenous populations; INSERTION-DELETION POLYMORPHISM; Intraspecific genetic variation; Linguistics; MBYÁ-GUARANÍ; Native Americans; Native North Americans; PILAGÁ; Polymorphism, Genetic - genetics; Population; Population biology; Population distributions; Population genetics; Samples; Stochastic Processes; TOBA; WICHÍ
• ISSN: 0018-7143; 1534-6617; 1534-6617
• DOI: 10.1353/hub.2007.0009

We studied five population samples from Argentina, four drawn from Native American groups of the northeast region (Wichí, Pilagá, Toba, and Mbyá-Guaraní) and one from two small villages of the Córdoba province. In this study we report genotypes and allele frequencies of the 9.1-kb insertion-deletion polymorphism located on chromosome 22. The frequency of the deletion allele ranges from 0.276 in the Mbyá-Guaraní to 0.470 in the Pilagá. The coefficient of population differentiation is fairly low (FST = 0.013), does not reflect any geographic or linguistic pattern, and seems to be more related to stochastic processes than to directional forces.