Bedside neuropathy disability score compared to quantitative sensory testing for measurement of diabetic neuropathy in children, adolescents, and young adults with type 1 diabetes

Abstract Background While regular yearly screening for diabetic retinopathy and nephropathy is well established in patients with diabetes mellitus, there are no standardized diagnostic tests for diabetic peripheral neuropathy (DPN). In the present study, we compared the bedside neuropathy disability...

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Bibliographic Details
Published in:Journal of diabetes and its complications 2007, Vol.21 (1), p.13-19
Main Authors: Weintrob, Naomi, Amitay, Iris, Lilos, Pearl, Shalitin, Shlomit, Lazar, Liora, Josefsberg, Zeev
Format: Article
Language:English
Subjects:
Adolescent
Adult
Child
Children & youth
Diabetes
Diabetes Mellitus, Type 1 - physiopathology
Diabetic Nephropathies - physiopathology
Diabetic neuropathy
Diabetic peripheral neuropathy
Diabetic retinopathy
Disability Evaluation
Disabled Persons
Endocrinology & Metabolism
Female
Glycated Hemoglobin A - analysis
HbA 1c
Humans
Israel
Male
Methods
Neuropathy disability score
Point-of-Care Systems
quantitative sensory testing
Reproducibility of Results
Sensory Thresholds
Vibration
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Summary:Abstract Background While regular yearly screening for diabetic retinopathy and nephropathy is well established in patients with diabetes mellitus, there are no standardized diagnostic tests for diabetic peripheral neuropathy (DPN). In the present study, we compared the bedside neuropathy disability score (NDS) with quantitative sensory testing (QST) for screening for DPN in youth with type 1 diabetes mellitus. Methods One hundred sixty-six patients aged 10 to 34 years (median 21 years) were evaluated for DPN by the NDS and QST. Quantitative sensory testing was also done in 43 healthy, age-matched controls. Diabetic peripheral neuropathy grade by both methods was correlated with disease-related variables. Results On QST, the diabetic group had significantly higher mean scores for vibration ( P
ISSN:1056-8727
1873-460X
DOI:10.1016/j.jdiacomp.2005.11.002