Mesenchymal Hamartoma of the Liver in a Late-Term Equine Fetus

Mesenchymal hamartoma of the liver is a rare congenital disorder of biliary tract development. During the necropsy of a late-term equine fetus, a markedly enlarged liver of more than two times normal weight was found. Light microscopic review revealed that the normal hepatic parenchyma had been obli...

Full description

Saved in:
Bibliographic Details
Published in:Veterinary pathology 2007, Vol.44 (1), p.100-102
Main Authors: Brown, D.L, Anderson, M, Cullen, J.M
Format: Article
Language:English
Subjects:
Animals
bile ducts
biliary tract diseases
congenital abnormalities
Fatal Outcome
Female
Fetus
hamartoma
Hamartoma - congenital
Hamartoma - pathology
Hamartoma - veterinary
Histocytochemistry - veterinary
histopathology
Horse Diseases - congenital
Horse Diseases - pathology
Horses
liver
Liver Diseases - congenital
Liver Diseases - pathology
Liver Diseases - veterinary
Pregnancy
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Mesenchymal hamartoma of the liver is a rare congenital disorder of biliary tract development. During the necropsy of a late-term equine fetus, a markedly enlarged liver of more than two times normal weight was found. Light microscopic review revealed that the normal hepatic parenchyma had been obliterated, replaced, and expanded by abnormal bile ducts surrounded by abundant, myxoid stroma. The lesion was diagnosed as a mesenchymal hamartoma. Small portions of the liver had bridging septa of fibrosis and proliferations of small-caliber abnormal bile ducts, resembling another congenital biliary abnormality termed congenital hepatic fibrosis.
ISSN:0300-9858
1544-2217
DOI:10.1354/vp.44-1-100