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Mesenchymal Hamartoma of the Liver in a Late-Term Equine Fetus

Mesenchymal hamartoma of the liver is a rare congenital disorder of biliary tract development. During the necropsy of a late-term equine fetus, a markedly enlarged liver of more than two times normal weight was found. Light microscopic review revealed that the normal hepatic parenchyma had been obli...

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Published in:	Veterinary pathology 2007, Vol.44 (1), p.100-102
Main Authors:	Brown, D.L, Anderson, M, Cullen, J.M
Format:	Article
Language:	English
Subjects:	Animals bile ducts biliary tract diseases congenital abnormalities Fatal Outcome Female Fetus hamartoma Hamartoma - congenital Hamartoma - pathology Hamartoma - veterinary Histocytochemistry - veterinary histopathology Horse Diseases - congenital Horse Diseases - pathology Horses liver Liver Diseases - congenital Liver Diseases - pathology Liver Diseases - veterinary Pregnancy
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creator	Brown, D.L Anderson, M Cullen, J.M
description	Mesenchymal hamartoma of the liver is a rare congenital disorder of biliary tract development. During the necropsy of a late-term equine fetus, a markedly enlarged liver of more than two times normal weight was found. Light microscopic review revealed that the normal hepatic parenchyma had been obliterated, replaced, and expanded by abnormal bile ducts surrounded by abundant, myxoid stroma. The lesion was diagnosed as a mesenchymal hamartoma. Small portions of the liver had bridging septa of fibrosis and proliferations of small-caliber abnormal bile ducts, resembling another congenital biliary abnormality termed congenital hepatic fibrosis.
doi_str_mv	10.1354/vp.44-1-100
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source	SAGE
subjects	Animals bile ducts biliary tract diseases congenital abnormalities Fatal Outcome Female Fetus hamartoma Hamartoma - congenital Hamartoma - pathology Hamartoma - veterinary Histocytochemistry - veterinary histopathology Horse Diseases - congenital Horse Diseases - pathology Horses liver Liver Diseases - congenital Liver Diseases - pathology Liver Diseases - veterinary Pregnancy
title	Mesenchymal Hamartoma of the Liver in a Late-Term Equine Fetus
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