Successful joint arthroplasty after treatment of destructive MRSA arthritis of the knee using antibiotic-loaded hydroxyapatite blocks: a case report

Methicillin-resistant Staphylococcus aureus (MRSA) septic arthritis is frequently associated with a poor clinical outcome. Joint reconstruction may be worth attempting in patients with a history of persistent MRSA infection. Here we report an unusual case of MRSA septic arthritis of the knee joint t...

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Bibliographic Details
Published in:Archives of orthopaedic and trauma surgery 2007-01, Vol.127 (1), p.47-50
Main Authors: Matsumoto, Kazu, Itokazu, Mansho, Uemura, Shuichi, Takigami, Iori, Naganawa, Toshitaka, Shimizu, Katsuji
Format: Article
Language:English
Subjects:
Aged
Anti-Bacterial Agents - therapeutic use
Antibiotics
Arthritis
Arthritis, Infectious - drug therapy
Arthritis, Infectious - surgery
Arthroplasty, Replacement, Knee - methods
Biocompatible Materials - therapeutic use
Case reports
Durapatite - therapeutic use
Female
Humans
Hydroxyapatite
Knee
Knee Joint - diagnostic imaging
Knee Joint - surgery
Methicillin Resistance
Radiography
Staphylococcal Infections - drug therapy
Staphylococcus infections
Vancomycin - therapeutic use
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Summary:Methicillin-resistant Staphylococcus aureus (MRSA) septic arthritis is frequently associated with a poor clinical outcome. Joint reconstruction may be worth attempting in patients with a history of persistent MRSA infection. Here we report an unusual case of MRSA septic arthritis of the knee joint that was treated successfully by joint replacement after initial placement of antibiotic-loaded hydroxyapatite (HA) blocks.
ISSN:0936-8051
1434-3916
DOI:10.1007/s00402-006-0212-8