Regular exercise attenuated lipid peroxidation in adolescents with Down's syndrome

This study was designed to ascertain whether regular exercise may attenuate lipid peroxidation in adolescents with Down's syndrome. Thirty-one male adolescents with Down's syndrome performed a 12-week training program, 3 days/week at a work intensity of 60–75% of peak heart rate (HRmax = 1...

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Bibliographic Details
Published in:Clinical biochemistry 2007, Vol.40 (1), p.141-142
Main Authors: Javier Ordonez, Francisco, Rosety-Rodriguez, Manuel
Format: Article
Language:English
Subjects:
Adolescent
Down Syndrome - blood
Down Syndrome - metabolism
Down's syndrome
Exercise
Exercise - physiology
Humans
Lipid Peroxidation
Male
Malondialdehyde
Malondialdehyde - blood
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Summary:This study was designed to ascertain whether regular exercise may attenuate lipid peroxidation in adolescents with Down's syndrome. Thirty-one male adolescents with Down's syndrome performed a 12-week training program, 3 days/week at a work intensity of 60–75% of peak heart rate (HRmax = 194.5–[0.56 age]). Plasmatic malondialdehyde (MDA) was determined by high performance liquid chromatography (HPLC). When compared to baseline, MDA content was decreased significantly. Regular exercise significantly decreased lipoperoxidation in Down's syndrome.
ISSN:0009-9120
1873-2933
DOI:10.1016/j.clinbiochem.2006.09.013