Prevalence of neonatal ultrasound brain lesions in premature infants with and without intrauterine growth restriction

Aim: To compare the prevalence of transient periventricular echodensities (TPE), periventricular leukomalacia (PVL) and haemorrhagic brain lesions (HBL) in singleton intrauterine growth‐restricted (IUGR) infants and in those appropriate for gestational age (AGA). Methods: Thirty‐five IUGR and 35 AGA...

Full description

Saved in:
Bibliographic Details
Published in:Acta Paediatrica 2007-11, Vol.96 (11), p.1582-1587
Main Authors: Padilla-Gomes, Nelly F, Enríquez, Goya, Acosta-Rojas, Ruthy, Perapoch, Josep, Hernandez-Andrade, Edgar, Gratacos, Eduard
Format: Article
Language:English
Subjects:
Biological and medical sciences
Cerebral Hemorrhage - diagnostic imaging
Cerebral Hemorrhage - epidemiology
Cerebral Ventricles - diagnostic imaging
Cerebral Ventricles - pathology
Epidemiology
Female
Fetal Growth Retardation - physiopathology
General aspects
Gestational Age
Haemorrhagic brain lesions
Humans
Infant, Newborn
Infant, Premature
Intensive Care Units, Neonatal - utilization
Intrauterine growth restriction
Leukomalacia, Periventricular - diagnostic imaging
Leukomalacia, Periventricular - epidemiology
Male
Medical sciences
Miscellaneous
Neurologic Examination
Periventricular leukomalacia
Preterm delivery
Prevalence
Prospective Studies
Public health. Hygiene
Public health. Hygiene-occupational medicine
Spain - epidemiology
Transient periventricular echodensities
Ultrasonography
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Aim: To compare the prevalence of transient periventricular echodensities (TPE), periventricular leukomalacia (PVL) and haemorrhagic brain lesions (HBL) in singleton intrauterine growth‐restricted (IUGR) infants and in those appropriate for gestational age (AGA). Methods: Thirty‐five IUGR and 35 AGA singleton infants born between 24‐ and 34‐week gestational age were studied. The presence of TPE, PVL and HBL was assessed with ultrasound (US) at day 3 (US‐I), 2 weeks (US‐II) after delivery and at term‐equivalent age (US‐III). Results: IUGR neonates had an increased prevalence of TPE at US‐I (18/35 vs. 8/35, p= 0.02) and an increased prevalence of PVL at US‐II (8/32 vs. 1/31, p = 0.03) and US‐III (8/29 vs. 1/29, p = 0.02). No significant differences in the prevalence of HBL were found between the two groups. Conclusions: IUGR is associated with an increased prevalence of white matter damage on US brain scans in preterm neonates.
ISSN:0803-5253
1651-2227
DOI:10.1111/j.1651-2227.2007.00496.x