A magnetic immunochromatographic strip test for detection of human papillomavirus 16 E6

Thus, an assay capable of detecting high-risk HPV E6 from cervical swab samples may have a high positive predictive value and may help to accurately identify women at increased risk of progression to cancer. Arbor Vita Corporation and PATH, a nonprofit, international health agency, have collaborated...

Full description

Saved in:
Bibliographic Details
Published in:Clinical chemistry (Baltimore, Md.) Md.), 2006-11, Vol.52 (11), p.2170-2172
Main Authors: Peck, Roger B, Schweizer, Johannes, Weigl, Bernhard H, Somoza, Chamorro, Silver, John, Sellors, John W, Lu, Peter S
Format: Article
Language:English
Subjects:
Antibodies, Monoclonal
Cervical cancer
Chromatography
Chromatography - methods
Electromagnetism
Enzyme-Linked Immunosorbent Assay
Female
Human papillomavirus
Human papillomavirus 16 - metabolism
Humans
Magnetics
Monoclonal antibodies
Oncogene Proteins, Viral - analysis
Oncogene Proteins, Viral - chemistry
Oncogene Proteins, Viral - immunology
PDZ Domains
Protein Binding
Protein Interaction Mapping
Proteins
Recombinant Fusion Proteins - chemistry
Repressor Proteins - analysis
Repressor Proteins - chemistry
Repressor Proteins - immunology
Sensitivity and Specificity
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Thus, an assay capable of detecting high-risk HPV E6 from cervical swab samples may have a high positive predictive value and may help to accurately identify women at increased risk of progression to cancer. Arbor Vita Corporation and PATH, a nonprofit, international health agency, have collaborated on the development of an assay based on the specific interaction of high-risk HPV E6 with PDZ protein and detection via an anti-HPV Eh monoclonal antibody.
ISSN:0009-9147
1530-8561
DOI:10.1373/clinchem.2006.072884