Microwave-Assisted Solid-Phase Peptide Synthesis Utilizing N-Fmoc-Protected (α-aminoacyl)benzotriazoles

A novel microwave‐assisted solid‐phase peptide synthesis utilizing N‐Fmoc‐protected(α‐aminoacyl)benzotriazoles was applied in the preparation of tri‐, tetra‐, penta‐, hexa‐, and heptapeptides in 71% average crude yield.

Saved in:
Bibliographic Details
Published in:Chemical biology & drug design 2007-11, Vol.70 (5), p.465-468
Main Authors: Katritzky, Alan R., Khashab, Niveen M., Yoshioka, Megumi, Haase, Danniebelle N., Wilson, Krista R., Johnson, Jodie V., Chung, Alfred, Haskell-Luevano, Carrie
Format: Article
Language:English
Subjects:
Benzene Derivatives - chemical synthesis
Benzene Derivatives - chemistry
microwave irradiation
Microwaves
Models, Molecular
Molecular Conformation
N-Fmoc-protected(α-aminoacyl)benzotriazole
peptides
Peptides - chemical synthesis
Peptides - chemistry
Rink amide resin
solid-phase peptide synthesis
Triazoles - chemical synthesis
Triazoles - chemistry
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:A novel microwave‐assisted solid‐phase peptide synthesis utilizing N‐Fmoc‐protected(α‐aminoacyl)benzotriazoles was applied in the preparation of tri‐, tetra‐, penta‐, hexa‐, and heptapeptides in 71% average crude yield.
ISSN:1747-0277
1747-0285
DOI:10.1111/j.1747-0285.2007.00584.x