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Microwave-Assisted Solid-Phase Peptide Synthesis Utilizing N-Fmoc-Protected (α-aminoacyl)benzotriazoles
A novel microwave‐assisted solid‐phase peptide synthesis utilizing N‐Fmoc‐protected(α‐aminoacyl)benzotriazoles was applied in the preparation of tri‐, tetra‐, penta‐, hexa‐, and heptapeptides in 71% average crude yield.
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Published in: | Chemical biology & drug design 2007-11, Vol.70 (5), p.465-468 |
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Main Authors: | , , , , , , , |
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cites | cdi_FETCH-LOGICAL-c4364-b2d52951ab0c15035b6dcb692e1f38cb119b5290d46ef1ccb7809651071428e83 |
container_end_page | 468 |
container_issue | 5 |
container_start_page | 465 |
container_title | Chemical biology & drug design |
container_volume | 70 |
creator | Katritzky, Alan R. Khashab, Niveen M. Yoshioka, Megumi Haase, Danniebelle N. Wilson, Krista R. Johnson, Jodie V. Chung, Alfred Haskell-Luevano, Carrie |
description | A novel microwave‐assisted solid‐phase peptide synthesis utilizing N‐Fmoc‐protected(α‐aminoacyl)benzotriazoles was applied in the preparation of tri‐, tetra‐, penta‐, hexa‐, and heptapeptides in 71% average crude yield. |
doi_str_mv | 10.1111/j.1747-0285.2007.00584.x |
format | article |
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source | Wiley-Blackwell Read & Publish Collection |
subjects | Benzene Derivatives - chemical synthesis Benzene Derivatives - chemistry microwave irradiation Microwaves Models, Molecular Molecular Conformation N-Fmoc-protected(α-aminoacyl)benzotriazole peptides Peptides - chemical synthesis Peptides - chemistry Rink amide resin solid-phase peptide synthesis Triazoles - chemical synthesis Triazoles - chemistry |
title | Microwave-Assisted Solid-Phase Peptide Synthesis Utilizing N-Fmoc-Protected (α-aminoacyl)benzotriazoles |
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