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Diagnostic and Therapeutic Challenges in Patients With Coexistent Chronic Obstructive Pulmonary Disease and Chronic Heart Failure

Diagnostic and Therapeutic Challenges in Patients With Coexistent Chronic Obstructive Pulmonary Disease and Chronic Heart Failure Thierry H. Le Jemtel, Margherita Padeletti, Sanja Jelic Chronic obstructive pulmonary disease (COPD) may delay the diagnosis of chronic heart failure (CHF), and promote n...

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Published in:Journal of the American College of Cardiology 2007-01, Vol.49 (2), p.171-180
Main Authors: Le Jemtel, Thierry H., MD, Padeletti, Margherita, MD, Jelic, Sanja, MD
Format: Article
Language:English
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Summary:Diagnostic and Therapeutic Challenges in Patients With Coexistent Chronic Obstructive Pulmonary Disease and Chronic Heart Failure Thierry H. Le Jemtel, Margherita Padeletti, Sanja Jelic Chronic obstructive pulmonary disease (COPD) may delay the diagnosis of chronic heart failure (CHF), and promote nonadherence to therapeutic guidelines, especially beta-blockade. Skeletal muscle alterations are strikingly similar in both conditions. Improvement of pulmonary or cardiac function does not translate into improved functional capacity unless skeletal muscle alterations concomitantly regress. Beta-blockade is safe in stable COPD. Beta -blockade should be attempted in all CHF patients with coexistent CHF and COPD.
ISSN:0735-1097
1558-3597
DOI:10.1016/j.jacc.2006.08.046