Microfluidic logic gates and timers

We use surface tension-based passive pumping and fluidic resistance to create a number of microfluidic analogs to electronic circuit components. Three classes of components are demonstrated: (1) OR/AND, NOR/NAND, and XNOR digital microfluidic logic gates; (2) programmable, autonomous timers; and (3)...

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Bibliographic Details
Published in:Lab on a chip 2007-01, Vol.7 (11), p.1449-1453
Main Authors: Toepke, Michael W, Abhyankar, Vinay V, Beebe, David J
Format: Article
Language:English
Subjects:
Microfluidics
Surface Tension
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Summary:We use surface tension-based passive pumping and fluidic resistance to create a number of microfluidic analogs to electronic circuit components. Three classes of components are demonstrated: (1) OR/AND, NOR/NAND, and XNOR digital microfluidic logic gates; (2) programmable, autonomous timers; and (3) slow, perfusive flow rheostats. The components can be implemented with standard pipettes and provide a means of non-electronic and autonomous preprogrammed control with potential utility in cell studies and high throughput screening applications.
ISSN:1473-0197
1473-0189
DOI:10.1039/b708764k