Undifferentiated Sebaceous Carcinoma: an Unusual Childhood Cancer

:  Sebaceous carcinoma is an aggressive, adnexal, rare malignant tumor that may arise in ocular or extra‐ocular sites. Extraorbital sebaceous carcinoma is exceptional in childhood. We report a 12‐year‐old boy with an ocular sebaceous carcinoma who was first seen with an asymptomatic firm, cutaneous...

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Bibliographic Details
Published in:Pediatric dermatology 2007-09, Vol.24 (5), p.501-504
Main Authors: Mebazaa, Amel, Boussofara, Lobna, Trabelsi, Amel, Denguezli, Mohamed, Sriha, Badreddine, Belajouza, Colandane, Nouira, Rafia
Format: Article
Language:English
Subjects:
Adenocarcinoma, Sebaceous - pathology
Adenocarcinoma, Sebaceous - surgery
Biological and medical sciences
Cell Differentiation
Child
Dermatology
Eyebrows - pathology
General aspects
Humans
Male
Medical sciences
Neoplasms, Adnexal and Skin Appendage - pathology
Neoplasms, Adnexal and Skin Appendage - surgery
Sebaceous Gland Neoplasms - pathology
Sebaceous Gland Neoplasms - surgery
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Summary::  Sebaceous carcinoma is an aggressive, adnexal, rare malignant tumor that may arise in ocular or extra‐ocular sites. Extraorbital sebaceous carcinoma is exceptional in childhood. We report a 12‐year‐old boy with an ocular sebaceous carcinoma who was first seen with an asymptomatic firm, cutaneous nodule on the right eyebrow. The tumor developed slowly within 1 year. Histologically, it was an undifferentiated sebaceous carcinoma. The patient had surgery with wide surgical margins. He was alive and free from disease at a follow‐up of 34 months. Close follow‐up of this tumor is recommended because of the risk of aggressive behavior.
ISSN:0736-8046
1525-1470
DOI:10.1111/j.1525-1470.2007.00503.x