When Two Is Better Than One

Gene duplication and divergence has long been considered an important route to adaptation and phenotypic evolution. Reporting in Nature, Hittinger and Carroll (2007) provide the first clear example of adaptations in both regulatory regions and protein-coding regions after gene duplication. This comb...

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Bibliographic Details
Published in:Cell 2007-10, Vol.131 (2), p.225-227
Main Authors: Babbitt, Courtney C., Haygood, Ralph, Wray, Gregory A.
Format: Article
Language:English
Subjects:
Adaptation, Physiological
Evolution, Molecular
Gene Duplication
Genetic Variation
Saccharomyces cerevisiae - genetics
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Summary:Gene duplication and divergence has long been considered an important route to adaptation and phenotypic evolution. Reporting in Nature, Hittinger and Carroll (2007) provide the first clear example of adaptations in both regulatory regions and protein-coding regions after gene duplication. This combination of evolutionary changes appears to have resolved an adaptive conflict, leading to increased organismal fitness.
ISSN:0092-8674
1097-4172
DOI:10.1016/j.cell.2007.10.001