Serum Lactate and Base Deficit as Predictors of Mortality After Ruptured Abdominal Aortic Aneurysm Repair

• Published in: European journal of vascular and endovascular surgery 2005-09, Vol.30 (3), p.263-266
• Main Authors: Singhal, R., Coghill, J.E., Guy, A., Bradbury, A.W., Adam, D.J., Scriven, J.M.
• Format: Article
• Language: English
• Subjects: Acid-Base Imbalance - blood; Acid-Base Imbalance - etiology; Aged; Aged, 80 and over; Aortic Aneurysm, Abdominal - blood; Aortic Aneurysm, Abdominal - mortality; Aortic Aneurysm, Abdominal - physiopathology; Aortic Aneurysm, Abdominal - surgery; Aortic Rupture - blood; Aortic Rupture - mortality; Aortic Rupture - physiopathology; Aortic Rupture - surgery; Base deficit; Blood Vessel Prosthesis Implantation; Female; Humans; Intensive Care Units; Lactate; Lactic Acid - blood; Male; Middle Aged; Postoperative Period; Predictive Value of Tests; Prognosis; Retrospective Studies; Ruptured aortic aneurysm; Survival Analysis; Treatment Outcome
• ISSN: 1078-5884; 1532-2165
• DOI: 10.1016/j.ejvs.2005.04.003

Whole body hypoperfusion and lower torso ischaemia-reperfusion contribute to post-operative organ dysfunction in patients undergoing repair of ruptured abdominal aortic aneurysm (AAA). Serum lactate and base deficit are markers of tissue ischaemia and are used to assess the adequacy of resuscitation. This study examines the prognostic value of immediate post-operative levels of serum lactate and base deficit in ruptured AAA. Thirty patients (24 men and 6 women of median age 74, range 51–85, years) who survived to at least 12h after ruptured AAA repair were studied retrospectively. The relationship between immediate post-operative lactate, base deficit and mortality was determined. Fifteen patients (50%) died, all from organ failure. An elevated lactate (>2.1mmol/l) and base deficit (