Magnitude and Patterns of Decline in Health and Function in 1 Year Affect Subsequent 5-Year Survival

• Published in: The journals of gerontology. Series A, Biological sciences and medical sciences Biological sciences and medical sciences, 2005-07, Vol.60 (7), p.894-900
• Main Authors: Perera, Subashan, Studenski, Stephanie, Chandler, Julie M., Guralnik, Jack M.
• Format: Article
• Language: English
• Subjects: Aged; Cause of Death - trends; Clinical outcomes; Female; Follow-Up Studies; Gerontology; Health risk assessment; Health Status Indicators; Humans; Male; Mortality; Motor Activity - physiology; Older people; Predictive Value of Tests; Prospective Studies; Risk Factors; ROC Curve; Survival Rate - trends; Time Factors; United States - epidemiology
• ISSN: 1079-5006; 1758-535X
• DOI: 10.1093/gerona/60.7.894

Background. Indicators of physical function and health status can predict important outcomes in older persons, but little is known about the meaning of change in these measures. This study assessed the magnitude and patterns of change occurring in 1 year in six measures of health and function and estimated the effects on survival for 5 years. Methods. This prospective cohort study was based in two health care systems. Data were collected during home visits at baseline and every 3 months for 1 year. Subsequent deaths occurring within 5 years were ascertained using the National Death Index. Results. Of 439 older adults, 88 (20%) died within the subsequent 5 years. The optimal magnitude of decline to predict 5-year mortality was 0.1 meters/second for gait speed, 1 point for the Short Physical Performance Battery, and 0.05 points for Euroqol. Independent contributions were found for decline in gait speed (p =.001 to.002), Short Physical Performance Battery (p =.014 to.026), global health (p