Is it time to prescribe statins to patients with calcified aortic stenosis?

Aortic stenosis (AS) is a common disease especially in the older population. It is associated with high mortality and morbidity. Recent data suggest that coronary artery disease and AS share common risk factors. Retrospective studies suggest that statins might slow the progression of AS but there ar...

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Bibliographic Details
Published in:The American heart journal 2005-07, Vol.150 (1), p.41-45
Main Authors: Rashidi, Arash, Adler, Dale S., Casscells, Ward, Madjid, Mohammad
Format: Article
Language:English
Subjects:
Aortic Diseases - complications
Aortic Diseases - drug therapy
Aortic Valve Stenosis - complications
Aortic Valve Stenosis - drug therapy
Biological and medical sciences
Calcinosis - complications
Calcinosis - drug therapy
Cardiology. Vascular system
Cholesterol
Drug therapy
Endocardial and cardiac valvular diseases
Heart
Humans
Hydroxymethylglutaryl-CoA Reductase Inhibitors - therapeutic use
Medical sciences
Mortality
Risk Factors
Statins
Studies
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Description
Summary:Aortic stenosis (AS) is a common disease especially in the older population. It is associated with high mortality and morbidity. Recent data suggest that coronary artery disease and AS share common risk factors. Retrospective studies suggest that statins might slow the progression of AS but there are no randomized clinical trial data available. It would seem that statins can be considered for medical treatment of AS; however, this needs to be investigated in future randomized clinical trials.
ISSN:0002-8703
1097-6744
DOI:10.1016/j.ahj.2005.01.021