Radiotherapy is effective in patients with glioblastoma multiforme with a limited prognosis and in patients above 70 years of age: A retrospective single institution analysis

To evaluate the efficacy of radiotherapy in patients with glioblastoma multiforme (GBM) with a limited prognosis and in patients older than 70 years. Retrospective analysis of 202 patients with GBM treated between 1990 and 2000 in a single institution. Patients (including patients ≥70 years) were as...

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Bibliographic Details
Published in:Radiotherapy and oncology 2005-05, Vol.75 (2), p.210-216
Main Authors: Marijnen, Corrie A.M., van den Berg, Sylvia M.P., van Duinen, Sjoerd G., Voormolen, Joan H.C., Noordijk, Ed M.
Format: Article
Language:English
Subjects:
Age Factors
Aged
Brain Neoplasms - radiotherapy
Elderly
Female
Glioblastoma - radiotherapy
Glioblastoma multiforme
Humans
Male
Middle Aged
Prognosis
Radiotherapy
Recursive partitioning analysis
Retrospective Studies
Survival
Survival Analysis
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Summary:To evaluate the efficacy of radiotherapy in patients with glioblastoma multiforme (GBM) with a limited prognosis and in patients older than 70 years. Retrospective analysis of 202 patients with GBM treated between 1990 and 2000 in a single institution. Patients (including patients ≥70 years) were assigned to RPA groups and their survival was compared with RTOG data. Median survival was 8.0 months for the total group and 13.9, 10.6, 3.8, 2.1 months for RPA group III (n=17), IV (n=87), V (n=60) and VI (n=38), respectively. Median survival for patients ≥70 years was 3.6 vs. 8.1 months for 50–70 years and 11.0 months for
ISSN:0167-8140
1879-0887
DOI:10.1016/j.radonc.2005.03.004