Ruthenium-Catalyzed [2 + 2] Cycloadditions of Ynamides

Ruthenium-catalyzed [2 + 2] cycloadditions between norbornene and ynamides were investigated. The ynamide moiety was found to be compatible with the ruthenium-catalyzed cycloaddition conditions, giving the corresponding cyclobutene cycloadducts in moderate to good yields (up to 97%).

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Bibliographic Details
Published in:Organic letters 2005-08, Vol.7 (17), p.3681-3684
Main Authors: Riddell, Nicole, Villeneuve, Karine, Tam, William
Format: Article
Language:English
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Summary:Ruthenium-catalyzed [2 + 2] cycloadditions between norbornene and ynamides were investigated. The ynamide moiety was found to be compatible with the ruthenium-catalyzed cycloaddition conditions, giving the corresponding cyclobutene cycloadducts in moderate to good yields (up to 97%).
ISSN:1523-7060
1523-7052
DOI:10.1021/ol0512841