Impact of assisted hatching on ART outcome in women with endometriosis

BACKGROUND: Assisted hatching can improve the implantation rate in cycles with poor outcome. The impact of assisted hatching in embryos from women with endometriosis is not known. Therefore, the hypothesis that the implantation potential of embryos obtained from women with endometriosis can be impro...

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Bibliographic Details
Published in:Human reproduction (Oxford) 2005-09, Vol.20 (9), p.2546-2549
Main Authors: Nadir Çıray, H., Bener, Faruk, Karagenç, Levent, Ulug, Ulun, Bahçeci, Mustafa
Format: Article
Language:English
Subjects:
Adult
assisted hatching
Biological and medical sciences
Birth control
Embryo Implantation
Endometriosis
Endometriosis - complications
Female
Female genital diseases
Gynecology. Andrology. Obstetrics
Humans
implantation
Infertility, Female - etiology
Infertility, Female - therapy
IVF outcomes
Medical sciences
Non tumoral diseases
Pregnancy
Pregnancy Outcome
Prospective Studies
Reproductive Techniques, Assisted
Sterility. Assisted procreation
Zona Pellucida
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Summary:BACKGROUND: Assisted hatching can improve the implantation rate in cycles with poor outcome. The impact of assisted hatching in embryos from women with endometriosis is not known. Therefore, the hypothesis that the implantation potential of embryos obtained from women with endometriosis can be improved with assisted hatching was tested. METHODS: In a prospective randomized study, transfer embryos obtained from 60 women with endometriosis were hatched using a laser system and compared to embryos obtained from patients with the same diagnosis which were left intact (n=30). RESULTS: The characteristics of cycles were similar between groups. The pregnancy (40% zona intact, 28.3% assisted hatching), and implantation rates (19.4% zona intact, 17.8% assisted hatching) did not differ in endometriosis cycles regardless of assisted hatching. CONCLUSION: Assisted hatching does not improve outcome in women with endometriosis undergoing assisted reproduction.
ISSN:0268-1161
1460-2350
DOI:10.1093/humrep/dei064