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DNA methyltransferases and structural-functional specificity of eukaryotic DNA modification
Properties of the main families of mammalian, plant, and fungal DNA methyltransferases are considered. Structural-functional specificity of eukaryotic genome sequences methylated by DNA methyltransferases is characterized. The total methylation of cytosine in DNA sequences is described, as well as i...
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Published in: | Biochemistry (Moscow) 2005-07, Vol.70 (7), p.730-742 |
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container_title | Biochemistry (Moscow) |
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creator | Buryanov, Ya I Shevchuk, T V |
description | Properties of the main families of mammalian, plant, and fungal DNA methyltransferases are considered. Structural-functional specificity of eukaryotic genome sequences methylated by DNA methyltransferases is characterized. The total methylation of cytosine in DNA sequences is described, as well as its relation with RNA interference. Mechanisms of regulation of expression and modulation of DNA methyltransferase activity in the eukaryotic cell are discussed. |
doi_str_mv | 10.1007/s10541-005-0178-0 |
format | article |
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subjects | Animals Deoxyribonucleic acid DNA DNA - chemistry DNA - genetics DNA - metabolism DNA methylation DNA Modification Methylases - chemistry DNA Modification Methylases - genetics DNA Modification Methylases - metabolism Eukaryotes Eukaryotic Cells - metabolism Gene Expression Regulation, Enzymologic Humans Methylation Methyltransferases Proteins Sensitivity and Specificity Sequence Analysis, DNA |
title | DNA methyltransferases and structural-functional specificity of eukaryotic DNA modification |
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