Activity of Chemotherapy in Mucinous Epithelial Ovarian Cancer: A Retrospective Study

Objective: Mucinous ovarian carcinoma has a poorer prognosis compared with other histological subtypes. The aim of this study was to evaluate, retrospectively, the activity of first-line and second-line chemotherapy in patients with mucinous ovarian cancer in a mono-institutional series. Patients an...

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Bibliographic Details
Published in:Anticancer research 2005-09, Vol.25 (5), p.3501-3505
Main Authors: PISANO, Carmela, GREGGI, Stefano, PIGNATA, Sandro, TAMBARO, Rosa, LOSITO, Simona, IODICE, Francesco, DI MAIO, Massimo, FERRARI, Ettore, FALANGA, Marzia, FORMATO, Roberta, IAFFAIOLI, Vincenzo Rosario
Format: Article
Language:English
Subjects:
Adenocarcinoma, Mucinous - drug therapy
Adenocarcinoma, Mucinous - pathology
Adult
Aged
Aged, 80 and over
Antineoplastic Combined Chemotherapy Protocols - therapeutic use
Biological and medical sciences
Carboplatin - administration & dosage
Cisplatin - administration & dosage
Epithelial Cells - pathology
Female
Female genital diseases
Gynecology. Andrology. Obstetrics
Humans
Medical sciences
Middle Aged
Neoplasm Staging
Ovarian Neoplasms - drug therapy
Ovarian Neoplasms - pathology
Paclitaxel - administration & dosage
Retrospective Studies
Tumors
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Summary:Objective: Mucinous ovarian carcinoma has a poorer prognosis compared with other histological subtypes. The aim of this study was to evaluate, retrospectively, the activity of first-line and second-line chemotherapy in patients with mucinous ovarian cancer in a mono-institutional series. Patients and Methods: In the period under survey (1996-2003), 225 new patients with ovarian cancer were treated. Twenty-one out of these patients (9.3%) received a diagnosis of mucinous ovarian cancer. The median age, performance status, stage at diagnosis and residual disease after surgery were similar in the mucinous compared to the other histological groups (P=NS). Results: In mucinous ovarian cancer the grading of the tumors was 2 in 76% of the cases, while grade 3 was more frequent in the other subtypes (p
ISSN:0250-7005
1791-7530