Effect of thermal energy produced by drilling on the facial nerve: histopathologic evaluation in guinea pigs

The effect of thermal energy due to drilling around the facial nerve canal on the facial nerve was histopathologically evaluated in four guinea pigs. The bony canal of the facial nerve was drilled using a 3mm diamond burr for one minute. The temperature changes on the facial nerve canalwere noted be...

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Bibliographic Details
Published in:Journal of laryngology and otology 2005-08, Vol.119 (8), p.600-605
Main Authors: Aslan, Asim, Vatansever, H Seda, Aslan, Gulay Guclu, Eskiizmir, Gorkem, Giray, Gulsen
Format: Article
Language:English
Subjects:
(RF) Otorhinolaryngology
Animals
Biological and medical sciences
Bones
Cadavers
Canals
Dissection
Drilling
Drinking water
Ethanol
Facial Nerve
Facial Nerve - pathology
Facial Nerve Injuries - etiology
Facial Nerve Injuries - pathology
Guinea Pigs
Heat
Histocytochemistry - methods
Hot Temperature - adverse effects
Immunohistochemistry - methods
Intraoperative Complications - pathology
Ketamine
Mastoid - surgery
Medical sciences
Models, Animal
Nitric oxide
Osteotomy - adverse effects
Otological Surgical Procedures
Otorhinolaryngology. Stomatology
Temperature
Thermal energy
Trauma
Wounds And Injuries
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Summary:The effect of thermal energy due to drilling around the facial nerve canal on the facial nerve was histopathologically evaluated in four guinea pigs. The bony canal of the facial nerve was drilled using a 3mm diamond burr for one minute. The temperature changes on the facial nerve canalwere noted before and after dissection. The temporal bones of the animals were histopathologically examined under light microscopy using haematoxylin & eosin (H&E) and solochrome cyanine staining for myelin, and immunohistochemical staining for neuronal nitric oxide synthase (nNOS). Compared to the control group, it was observed with H&E staining that there was oedema among the axonal fibres and with solochrome cyanine staining that the thickness of the myelin fibres was decreased, and that the severity and extent of nNOS activity was decreased in the axonal fibres. It was concluded that a temperature increase on the facial canal may potentially lead to inflammation of the nerve, and may also cause deterioration of nerve conduction to some extent.
ISSN:0022-2151
1748-5460
DOI:10.1258/0022215054516250