Post-infectious irritable bowel syndrome

Irritable bowel syndrome (IBS) is a common disorder associated with abdominal pain or discomfort and altered bowel habits. The majority of patients describe an insidious onset of symptoms; however, a subset report a fairly precise time of onset following an attack of acute gastroenteritis. Typically...

Full description

Saved in:
Bibliographic Details
Published in:Current gastroenterology reports 2007-10, Vol.9 (5), p.378-384
Main Author: Dupont, Andrew W
Format: Article
Language:English
Subjects:
Anti-Inflammatory Agents, Non-Steroidal - therapeutic use
Bacterial Infections - complications
Bacterial Infections - microbiology
Biological Therapy - methods
Combined Modality Therapy
Disease Progression
Enterocolitis - complications
Enterocolitis - microbiology
Female
Humans
Incidence
Irritable bowel syndrome
Irritable Bowel Syndrome - epidemiology
Irritable Bowel Syndrome - etiology
Irritable Bowel Syndrome - therapy
Male
Prognosis
Randomized Controlled Trials as Topic
Severity of Illness Index
Treatment Outcome
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Irritable bowel syndrome (IBS) is a common disorder associated with abdominal pain or discomfort and altered bowel habits. The majority of patients describe an insidious onset of symptoms; however, a subset report a fairly precise time of onset following an attack of acute gastroenteritis. Typically, the potential acute infectious symptoms, such as fever and vomiting, resolve after several days, but abdominal discomfort, bloating, and diarrhea persist. Although the underlying mechanism of post-infectious IBS (PI-IBS) has not been established, ongoing inflammation appears to play a role, with an increase in serotonin-containing enterochromaffin cells, T lymphocytes, mast cells, proinflammatory cytokines, and intestinal permeability. Psychiatric comorbidities are less common in PI-IBS, compared with IBS patients in general; however, the prevalence of psychological disorders is still higher compared with that in the general population and is associated with a poorer prognosis. Overall, patients with PI-IBS have a slightly improved prognosis compared with those with IBS without an infectious onset.
ISSN:1522-8037
1534-312X
DOI:10.1007/s11894-007-0046-8