Adult onset tubulointerstitial nephritis and uveitis syndrome

A Turkish woman aged 44 years who presented with a 1 month history of abdominal pain, fatigue and weight loss of 10 kg was diagnosed as having acute tubulointerstitial nephritis. Opthalmological evaluation revealed unilateral uveitis and contralateral chorioretinal scarring. X‐ray films of the pelvi...

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Bibliographic Details
Published in:Nephrology (Carlton, Vic.) Vic.), 2005-08, Vol.10 (4), p.418-420
Main Authors: KAYNAR, KUBRA, ERSOZ, SAFAK, AKYOL, NURETTIN, ERSOZ, ONDER, UNLU, OZGE, OZBAY, TULIN, ULUSOY, SUKRU
Format: Article
Language:English
Subjects:
acute tubulointerstitial nephritis
Adult
Alleles
Female
HLA-DR Antigens - genetics
HLA-DRB1 Chains
Humans
Nephritis, Interstitial - complications
Nephritis, Interstitial - diagnosis
Nephritis, Interstitial - genetics
sacroileitis
Syndrome
unilateral uveitis
Uveitis - complications
Uveitis - diagnosis
Uveitis - genetics
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Summary:A Turkish woman aged 44 years who presented with a 1 month history of abdominal pain, fatigue and weight loss of 10 kg was diagnosed as having acute tubulointerstitial nephritis. Opthalmological evaluation revealed unilateral uveitis and contralateral chorioretinal scarring. X‐ray films of the pelvis revealed unilateral sacroileitis. An elevated erythrocyte sedimentation rate, C‐reactive protein, tubular proteinuria and renal glucosuria returned to normal 2 weeks after treatment was started. It is important to be aware of tubulointerstitial nephritis and uveitis syndrome in order to achieve a quick diagnosis in patients with renal impairment and tubular dysfunction with minor symptoms so that appropriate management can be started early.
ISSN:1320-5358
1440-1797
DOI:10.1111/j.1440-1797.2005.00400.x