Impact of electrical neurostimulation on persistent ST elevation after successful reperfusion by primary percutaneous coronary intervention

Abstract Aims To study the effect of electrical neurostimulation on the ST segment shift in patients with ST elevation myocardial infarction (STEMI) with residual ST elevation after primary percutaneous coronary intervention (PCI). Methods After primary PCI, 38 patients with STEMI were divided into...

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Published in:Journal of electrocardiology 2007-11, Vol.40 (6), p.522-526
Main Authors: de Vries, Jessica, MD, Svilaas, Tone, MD, DeJongste, Mike J.L., MD, PhD, FESC, Nieuwland, Wybe, MD, PhD, Hoekstra-Mars, Erna W., BSc, Zijlstra, Felix, MD, PhD, FESC, FACC
Format: Article
Language:English
Subjects:
Angioplasty, Balloon - adverse effects
Atrial Fibrillation - diagnosis
Atrial Fibrillation - etiology
Atrial Fibrillation - prevention & control
Cardiovascular
Electric Stimulation Therapy - methods
Electrical stimulation
Electrocardiography
Female
Humans
Male
Middle Aged
PCI
STEMI
Treatment Outcome
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Summary:Abstract Aims To study the effect of electrical neurostimulation on the ST segment shift in patients with ST elevation myocardial infarction (STEMI) with residual ST elevation after primary percutaneous coronary intervention (PCI). Methods After primary PCI, 38 patients with STEMI were divided into 2 groups. Group 1 received 15 minutes of active neurostimulation after the baseline electrocardiogram (ECG); group 2 received 15 minutes of active neurostimulation after 15 minutes of nonactive neurostimulation. Results In group 1, ST elevation decreased with neurostimulation from 0.65 ± 0.56 to 0.55 ± 0.51 ( P = .02) and to 0.50 ± 0.52 ( P = .01) without electrical neurostimulation. In group 2, ST elevation changed without neurostimulation from 0.37 ± 0.32 to 0.33 ± 0.30 ( P = NS) and to 0.28 ± 0.27 ( P = .01) with electrical neurostimulation. In a posthoc analysis, 17 responders had higher ST elevation at the ECG before active electrical neurostimulation than 21 nonresponders ( P = .001). Conclusion Electrical neurostimulation may result in significant additional reduction of ST elevation in STEMI after reperfusion treatment, in particular in patients with marked ST elevation on the first ECG after successful primary PCI.
ISSN:0022-0736
1532-8430
DOI:10.1016/j.jelectrocard.2007.05.014