Central venous catheter-related infection due to Candida membranaefaciens, a new opportunistic azole-resistant yeast in a cancer patient: a case report and a review of literature

Summary An unusual central venous catheter (CVC)‐related infection caused by Candida membranaefaciens in a patient with non‐Hodgkin's lymphoma is described. Clinical signs and microbiological results observed in this case may support the hypothesis of an emerging CVC‐related fungaemia, because...

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Bibliographic Details
Published in:Mycoses 2005-09, Vol.48 (5), p.357-359
Main Authors: Fanci, Rosa, Pecile, Patrizia
Format: Article
Language:English
Subjects:
Amphotericin B - therapeutic use
Antifungal Agents - therapeutic use
cancer patients
Candida - isolation & purification
Candida membranaefaciens
Candidiasis - prevention & control
Catheterization, Central Venous
central venous catheter infection
Drug Resistance, Fungal
Hodgkin Disease - complications
Humans
liposomal amphotericin B
Opportunistic Infections - microbiology
Opportunistic Infections - prevention & control
Prosthesis-Related Infections - microbiology
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Summary:Summary An unusual central venous catheter (CVC)‐related infection caused by Candida membranaefaciens in a patient with non‐Hodgkin's lymphoma is described. Clinical signs and microbiological results observed in this case may support the hypothesis of an emerging CVC‐related fungaemia, because of new azole‐resistant yeast, successfully treated with liposomal amphotericin B. To date C. membranaefaciens (the teleomorph of Pichia membranaefaciens) has traditionally been considered non‐pathogenic and this report seems to be the first case of systemic fungal infection. We believe that another fungus can be added to the list of opportunistic strains.
ISSN:0933-7407
1439-0507
DOI:10.1111/j.1439-0507.2005.01133.x