Analysis of associations of NAT2 gene polymorphisms with the risk of lung cancer

The incidence of 5 polymorphisms of N-acetyltransferase-2 gene was evaluated in patients with lung cancer. A803G polymorphism is a factor of lung cancer resistance in tobacco smoking Caucasians in Novosibirsk. Opposite effects of NAT2 gene polymorphisms on the risk of lung cancer are possible.

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Bibliographic Details
Published in:Bulletin of experimental biology and medicine 2007-01, Vol.143 (1), p.83-86
Main Authors: Nikishina, M V, Vavilin, V A, Makarova, S I, Lyakhovich, V V
Format: Article
Language:English
Subjects:
Arylamine N-Acetyltransferase - genetics
Case-Control Studies
European Continental Ancestry Group
Female
Genetic Predisposition to Disease
Humans
Lung cancer
Lung Neoplasms - etiology
Lung Neoplasms - genetics
Lung Neoplasms - metabolism
Male
Middle Aged
Polymorphism, Genetic
Risk
Siberia
Smoking - adverse effects
Smoking - genetics
Smoking - metabolism
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Description
Summary:The incidence of 5 polymorphisms of N-acetyltransferase-2 gene was evaluated in patients with lung cancer. A803G polymorphism is a factor of lung cancer resistance in tobacco smoking Caucasians in Novosibirsk. Opposite effects of NAT2 gene polymorphisms on the risk of lung cancer are possible.
ISSN:0007-4888
1573-8221
DOI:10.1007/s10517-007-0023-0