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Correlation Between Distal Left Anterior Descending Artery Flow Velocity by Transthoracic Doppler Echocardiography and Corrected TIMI Frame Count Before Mechanical Reperfusion in Patients With Anterior Acute Myocardial Infarction

Background This study was designed to determine the utility of transthoracic Doppler echocardiography (TTDE) in evaluating angiographic Thrombolysis in Myocardial Infarction (TIMI) frame count as a quantitative index of coronary reperfusion in patients with anterior acute myocardial infarction (AMI)...

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Published in:Circulation Journal 2005, Vol.69(9), pp.1022-1028
Main Authors: Lee, Souki, Otsuji, Yutaka, Minagoe, Shinichi, Hamasaki, Shuichi, Toyonaga, Koichi, Obata, Hachiro, Takumi, Takuro, Arimura, Hiroshi, Miyata, Masaaki, Biro, Sadatoshi, Toda, Hitoshi, Tei, Chuwa
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Language:English
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Summary:Background This study was designed to determine the utility of transthoracic Doppler echocardiography (TTDE) in evaluating angiographic Thrombolysis in Myocardial Infarction (TIMI) frame count as a quantitative index of coronary reperfusion in patients with anterior acute myocardial infarction (AMI) before mechanical reperfusion. Methods and Results Color and pulsed TTDE was performed to evaluate distal left anterior descending coronary artery (LAD) reperfusion in 56 consecutive patients with a first anterior AMI before coronary intervention, and these findings were compared with the corrected TIMI frame count (cTFC) by subsequent angiography. Twenty-four of the 56 patients had LAD reperfusion (TIMI 2 or 3) by angiography. Visual antegrade distal LAD flow by color TTDE was detected in 21 of these 24 patients. In the 21 patients, diastolic peak velocity of the distal LAD flow by pulsed TTDE showed a significant correlation with cTFC by angiography (r=-0.74, p40 by distal LAD peak velocity
ISSN:1346-9843
1347-4820
DOI:10.1253/circj.69.1022