Planum Temporale Volume in Children and Adolescents with Autism

Previous research has revealed a lack of planum temporale (PT) asymmetry in adults with autism. This finding is now extended to children and adolescents with the disorder. MRI scans were obtained from 12 children with autism and 12 gender, handedness and age-matched comparison participants. The volu...

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Bibliographic Details
Published in:Journal of autism and developmental disorders 2005-08, Vol.35 (4), p.479-486
Main Authors: Rojas, Donald C, Camou, Suzanne L, Reite, Martin L, Rogers, Sally J
Format: Article
Language:English
Subjects:
Adolescent
Adolescents
Auditory Cortex - abnormalities
Auditory Cortex - physiopathology
Autism
Autistic Disorder - physiopathology
Biological and medical sciences
Brain
Brain Hemisphere Functions
Child
Child clinical studies
Child, Preschool
Children
Clinical Diagnosis
Control Groups
Developmental disorders
Diagnostic Tests
Female
Functional Laterality - physiology
Handedness
Humans
Infantile autism
Intellect
Intelligence
Intelligence levels
Language Acquisition
Language Skills
Magnetic Resonance Imaging
Male
Medical sciences
Neurodevelopmental disorders
Psychology. Psychoanalysis. Psychiatry
Psychopathology. Psychiatry
Temporal Lobe - abnormalities
Temporal Lobe - physiopathology
Temporal lobes
Time Factors
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Description
Summary:Previous research has revealed a lack of planum temporale (PT) asymmetry in adults with autism. This finding is now extended to children and adolescents with the disorder. MRI scans were obtained from 12 children with autism and 12 gender, handedness and age-matched comparison participants. The volume of gray matter in the PT and Heschl's gyrus (HG) in both hemispheres was measured. PT volume was larger in the left hemisphere than in the right in the comparison, but not the autism group. This specifically reflected reduced volume of the left PT in the autism group. There were noted differences in the overall morphological appearance of the right Sylvian fissure in the autism group, but no volumetric difference in the right PT. No differences in HG volumes were observed between the two groups. Lack of PT asymmetry may suggest an early neurodevelopmental disturbance in autism.
ISSN:0162-3257
1573-3432
DOI:10.1007/s10803-005-5038-7