Fibrinolysis in coronary artery surgery: detection by thromboelastography

• Published in: Interactive cardiovascular and thoracic surgery 2007-12, Vol.6 (6), p.700-704
• Main Authors: Vanek, Tomas, Jares, Martin, Snircova, Jana, Maly, Marek
• Format: Article
• Language: English
• Subjects: Anastomosis, Surgical; Biocompatible Materials; Blood Loss, Surgical - prevention & control; Cardiopulmonary Bypass - instrumentation; Coronary Artery Bypass; Coronary Artery Bypass, Off-Pump; Equipment Design; Erythrocyte Transfusion; Fibrin Fibrinogen Degradation Products - metabolism; Fibrinolysis; Humans; Myocardial Ischemia - blood; Myocardial Ischemia - surgery; Prospective Studies; Thrombelastography; Time Factors; Treatment Outcome
• ISSN: 1569-9293; 1569-9285
• DOI: 10.1510/icvts.2007.161463

a Department of Cardiac Surgery, 3rd Faculty of Medicine, Charles University Prague and University Hospital Kralovske Vinohrady, Czech Republic b Department of Biostatistics and Informatics, National Institute of Public Health, Prague, Czech Republic *Corresponding author. Department of Cardiac Surgery, FNKV, Srobarova 50, 100 34 Prague 10, Czech Republic. Tel.: [phone]; fax: [phone]. E-mail address : vanek{at}fnkv.cz (T. Vanek). Sixty-five patients scheduled for coronary surgery were randomized into three groups: A – conventional coronary artery bypass grafting, B – off-pump surgery, C – coronary artery bypass grafting with modified, rheoparin coated cardiopulmonary bypass with the avoidance of re-infusion of cardiotomy blood into the circuit. On the completion of peripheral bypass anastomoses, highly significant inter-group differences were found in the thromboelastographic parameter lysis of set time at 60 min of assessment ( P =0.003) and at 150 min of assessment ( P